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NUDCD1 抗体 (AA 431-530) (AbBy Fluor® 647)

This anti-NUDCD1 antibody is a 兔 多克隆 antibody detecting NUDCD1 in WB, IF (cc) 和 IF (p). Suitable for 小鼠.
产品编号 ABIN6980207
发货至: 中国

Quick Overview for NUDCD1 抗体 (AA 431-530) (AbBy Fluor® 647) (ABIN6980207)

抗原

NUDCD1 (NudC Domain Containing 1 (NUDCD1))

适用

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小鼠

宿主

  • 32

克隆类型

  • 32
多克隆

标记

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This NUDCD1 antibody is conjugated to AbBy Fluor® 647

应用范围

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Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

    • 14
    • 7
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    AA 431-530

    交叉反应

    小鼠

    预测反应

    Human,Rat,Dog,Cow,Sheep,Horse,Rabbit,Zebrafish

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human NUDCD1

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    NUDCD1 (NudC Domain Containing 1 (NUDCD1))

    别名

    NUDCD1

    背景

    Synonyms: 4921532K09Rik, AA407246, AW260430, AW556235, Chronic myelogenous leukemia tumor antigen 66, CML66, CML66 L, FLJ14991, NudC domain containing 1, NudC domain-containing protein 1, NUDC1_HUMAN, nudcd1, OVA66, RGD1310624, Tumor antigen CML66.

    Background: The NUDCD1 gene encodes the 583 amino acid CML66 protein which demonstrates expression in a variety of solid tumor cell lines and leukemias. Expression of CML66 in normal tissues is restricted to testis and heart. The CML66 antibody is found in sera of 18-38 % of patients with lung cancer, melanoma or prostate cancer. These findings indicate that CML66 may be immunogenic in a wide variety of malignancies and may be a target for antigen-specific immunotherapy. A short isoform of CML66, designated CML66-S, is a product of alternative splicing. CML66-S has the same C-terminus as full-lenghth CML66 (also designated CML66-L), but has a unique N-terminus. CML66-S shows predominant expression in testis, and is also expressed in very low levels in tumor cells, while CML66 is expressed in tumor cells and testis.

    基因ID

    84955

    UniProt

    Q96RS6
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