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STK24 抗体 (pThr178) (AbBy Fluor® 647)

This anti-STK24 antibody is a 兔 多克隆 antibody detecting STK24 in WB, IF (cc) 和 IF (p). Suitable for 小鼠 和 大鼠.
产品编号 ABIN6979800
发货至: 中国

Quick Overview for STK24 抗体 (pThr178) (AbBy Fluor® 647) (ABIN6979800)

抗原

See all STK24 抗体
STK24 (serine/threonine Kinase 24 (STK24))

适用

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  • 36
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  • 1
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  • 1
小鼠, 大鼠

宿主

  • 61
  • 9

克隆类型

  • 61
  • 9
多克隆

标记

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  • 1
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This STK24 antibody is conjugated to AbBy Fluor® 647

应用范围

  • 52
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  • 20
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  • 3
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  • 1
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Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

    • 14
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    pThr178

    交叉反应

    小鼠, 大鼠

    预测反应

    Human,Cow,Sheep,Horse

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthesised phosphopeptide derived from human MST3 around the phosphorylation site of Thr178

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    STK24 (serine/threonine Kinase 24 (STK24))

    别名

    MST3

    背景

    Synonyms: MST3 (phospho T178), p-MST3 (phospho T178), Kinase responsive to stress 1, KRS1, Mammalian STE20 like protein kinase 2, Mammalian sterile 20-like 2, Mess1, MST, MST-2, MST2, Mst3, Serine/threonine kinase 3 (STE20 homolog, yeast), Serine/threonine kinase 3 (Ste20, yeast homolog), Serine/threonine protein kinase 3, Serine/threonine protein kinase Krs1, STE20 like kinase MST2.

    Background: Serine/threonine-protein kinase that acts on both serine and threonine residues and promotes apoptosis in response to stress stimuli and caspase activation. Mediates oxidative-stress-induced cell death by modulating phosphorylation of JNK1-JNK2 (MAPK8 and MAPK9), p38 (MAPK11, MAPK12, MAPK13 and MAPK14) during oxidative stress. Plays a role in a staurosporine-induced caspase-independent apoptotic pathway by regulating the nuclear translocation of AIFM1 and ENDOG and the DNase activity associated with ENDOG. Phosphorylates STK38L on 'Thr-442' and stimulates its kinase activity. Regulates cellular migration with alteration of PTPN12 activity and PXN phosphorylation: phosphorylates PTPN12 and inhibits its activity and may regulate PXN phosphorylation through PTPN12. May act as a key regulator of axon regeneration in the optic nerve and radial nerve.

    基因ID

    8428

    UniProt

    Q9Y6E0
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