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MYST1 抗体 (AA 351-450) (AbBy Fluor® 647)

This anti-MYST1 antibody is a 兔 多克隆 antibody detecting MYST1 in WB, IF (cc) 和 IF (p). Suitable for 人 和 小鼠.
产品编号 ABIN6979779
发货至: 中国

Quick Overview for MYST1 抗体 (AA 351-450) (AbBy Fluor® 647) (ABIN6979779)

抗原

See all MYST1 (KAT8) 抗体
MYST1 (KAT8) (K(lysine) Acetyltransferase 8 (KAT8))

适用

  • 58
  • 47
  • 30
  • 2
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  • 1
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  • 1
  • 1
  • 1
人, 小鼠

宿主

  • 67
  • 6

克隆类型

  • 56
  • 17
多克隆

标记

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  • 2
  • 2
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  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
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This MYST1 antibody is conjugated to AbBy Fluor® 647

应用范围

  • 57
  • 26
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  • 23
  • 14
  • 9
  • 7
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  • 6
  • 6
  • 3
  • 1
  • 1
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Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

    • 15
    • 14
    • 7
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 351-450

    交叉反应

    人, 小鼠

    预测反应

    Rat,Cow,Sheep,Pig,Horse,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human MYST1/KAT8

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    MYST1 (KAT8) (K(lysine) Acetyltransferase 8 (KAT8))

    别名

    MYST1/KAT8

    背景

    Synonyms: EC 2.3.1.48, Histone acetyltransferase KAT8, Histone acetyltransferase MYST1, hMOF, K(lysine) acetyltransferase 8, KAT 8, Lysine acetyltransferase 8, MOF, MOZ, MOZ, YBF2/SAS3, SAS2 and TIP60 protein 1, MYST 1, MYST histone acetyltransferase 1, myst protein 1, MYST-1, MYST1, MYST1_HUMAN, Ortholog of Drosophila males absent on the first (MOF), Probable histone acetyltransferase MYST1, SAS2 and TIP60 protein 1, SAS2, SAS3, TIP60 protein 1, YBF2, YBF2/SAS3.

    Background: Dosage compensation ensures that males with a single X chromosome and females with two X chromosomes have the same amount of most X-linked gene products. In Drosophila, this is acheived by enhancing the level of transcription of the X chromosome in males. Proteins such as maleless, male specific lethal 1, 2 and 3, and males absent on the first (MOF) form a dosage compensation complex (DCC) that is required for the twofold increase of transcription of the male X chromosome. The DCC is preferentially associated with many sites on the X chromosome in somatic cells of males. The binding of the DCC to the X chromosome is dependent upon histone 4 acetylation at lysine 16, which is accomplished by MOF. In mammals, MOF (also designated hMOF, MYST1, or MOZ) belongs to the MYST family of histone acetyl transferases which are characterized by a unique C2HC-type zinc finger close to their HAT domains. MOF utilizes the zinc finger domain to contact the globular part of the nucleosome as well as the histone H4 N-terminal tail substrate. The carboxy terminal domain of human MOF also has histone acetyltransferase activity directed against histones H3 and H2A, a characteristic shared with other MYST family histone acetyltransferases.

    基因ID

    84148

    UniProt

    Q9H7Z6
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