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GPC1 抗体 (AA 251-350) (AbBy Fluor® 594)

This anti-GPC1 antibody is a 兔 多克隆 antibody detecting GPC1 in IF (cc) 和 IF (p). Suitable for 大鼠.
产品编号 ABIN6979544
发货至: 中国

Quick Overview for GPC1 抗体 (AA 251-350) (AbBy Fluor® 594) (ABIN6979544)

抗原

See all GPC1 抗体
GPC1 (Glypican 1 (GPC1))

适用

  • 59
  • 17
  • 16
大鼠

宿主

  • 71
  • 10
  • 2
  • 1

克隆类型

  • 71
  • 11
  • 1
多克隆

标记

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  • 1
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  • 1
  • 1
  • 1
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This GPC1 antibody is conjugated to AbBy Fluor® 594

应用范围

  • 39
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  • 17
  • 9
  • 9
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Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

    • 15
    • 14
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
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    • 1
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    • 1
    AA 251-350

    交叉反应

    大鼠

    预测反应

    Mouse,Dog,Cow,Sheep,Horse

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from mouse Glypican 1

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    GPC1 (Glypican 1 (GPC1))

    别名

    Glypican 1

    背景

    Synonyms: FLJ38078, glypican, glypican1, GPC 1, Glypican-1, GPC1, Glypican proteoglycan 1, Gpc1, GPC1_HUMAN, Secreted glypican-1.

    Background: Cell surface proteoglycan that bears heparan sulfate. Binds, via the heparan sulfate side chains, alpha-4 (V) collagen and participates in Schwann cell myelination (By similarity). May act as a catalyst in increasing the rate of conversion of prion protein PRPN(C) to PRNP(Sc) via associating (via the heparin sulfate side chains) with both forms of PRPN, targeting them to lipid rafts and facilitating their interaction. Required for proper skeletal muscle differentiation by sequestering FGF2 in lipid rafts preventing its binding to receptors (FGFRs) and inhibiting the FGF-mediated signaling.

    基因ID

    14733

    UniProt

    Q9QZF2

    途径

    Glycosaminoglycan Metabolic Process, Regulation of Muscle Cell Differentiation
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