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SUZ12 抗体 (C-Term)

This 兔 多克隆 antibody specifically detects SUZ12 in WB, IF, ChIP 和 ChIP-seq. It exhibits reactivity toward 人 和 小鼠.
产品编号 ABIN6972836
发货至: 中国
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Quick Overview for SUZ12 抗体 (C-Term) (ABIN6972836)

抗原

See all SUZ12 抗体
SUZ12 (SUZ12 Polycomb Repressive Complex 2 Subunit (SUZ12))

适用

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人, 小鼠

宿主

  • 54
  • 9

克隆类型

  • 32
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多克隆

标记

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This SUZ12 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Chromatin Immunoprecipitation (ChIP), ChIP DNA-Sequencing (ChIP-seq)
  • 抗原表位

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    C-Term

    产品特性

    Suz12 (Suppressor-of-Zeste 12 protein, also designated as ChET9, JJAZ1 protein) is a component of the Polycomb group complexes 2, 3 and 4 (PRC2, PRC3 and PRC4), which also contain the histone methyltransferase EZH2, EED (Embryonic Ectoderm Development protein) protein and the histone-binding proteins RbAP46 and RbAP48. PRC2 is responsible for di- and trimethylation of histone 3 at lysine 27 (Histone H3K27me2 and Histone H3K27me3), which leads to transcriptional repression of the target genes. Suz12 is a nuclear protein belonging to the VEFS family. Suz12 contains a zinc-finger binding motif and a VEFS box, which is required for the interaction between Suz12 and EZH2. Suz12 antibody (pAb) was raised in a Rabbit host. It has been validated for use in Chromatin Immunoprecipitation, ChIP-Seq, Immunofluorescence and Western blot, it has been shown to react with Human and Mouse samples.

    纯化方法

    Affinity Purified

    免疫原

    This Suz12 antibody was raised against a peptide corresponding to the C-terminus of human Suz12.

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 缓冲液

    PBS, 30 % glycerol, 0.035 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
  • 抗原

    SUZ12 (SUZ12 Polycomb Repressive Complex 2 Subunit (SUZ12))

    别名

    Suz12

    分子量

    95 kDa

    NCBI登录号

    NP_056170
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