SMC4 抗体 (N-Term)
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Quick Overview for SMC4 抗体 (N-Term) (ABIN6972758)
抗原
See all SMC4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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产品特性
- The Structural Maintenance of Chromosomes (SMC) family proteins play critical roles in various nuclear events that require structural changes of chromosomes, including mitotic chromosome organization, DNA recombination and repair and global transcriptional repression. SMC4 is the central component of the condensin complex, a complex required for conversion of interphase chromatin into condensed mitotic chromosomes. SMC4 forms a heterodimer with SMC2 and contains a myosin-like ATPase domain that serves as a molecular motor to help organize chromatin. During mitosis, most of the condensin complex is associated with the chromatin. SMC4 antibody (pAb) was raised in a Rabbit host. It has been validated for use in Immunoprecipitation and Western blot, it has been shown to react with Human samples.
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纯化方法
- Affinity Purified
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免疫原
- This SMC4 antibody was raised against a peptide from the N-terminus of human SMC4.
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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缓冲液
- Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
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- SMC4 (Structural Maintenance of Chromosomes 4 (SMC4))
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别名
- SMC4
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分子量
- 175 kDa
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NCBI登录号
- NP_001002800
抗原
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