SMC3 抗体 (C-Term)
Quick Overview for SMC3 抗体 (C-Term) (ABIN6972756)
抗原
See all SMC3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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产品特性
- The Structural Maintenance of Chromosomes (SMC) family proteins play critical roles in various nuclear events that require structural changes of chromosomes, including mitotic chromosome organization, DNA recombination and repair and global transcriptional repression. SMC3 is a component of the cohesin complex that plays an essential role during chromatid segregation. SMC3 is also involved in DNA recombination and repair, mitotic chromosome organization and microtubule-mediated intracellular transport. SMC3 is acetylated during replication, which is essential for cohesion, and is phosphorylated by ATM subsequent to DNA double strand breakage. SMC3 is frequently elevated in human colon carcinoma and overexpression of the protein transforms fibroblasts. SMC3 antibody (pAb) was raised in a Rabbit host. It has been validated for use in Western blot, it has been shown to react with Human samples.
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纯化方法
- Affinity Purified
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免疫原
- This SMC3 antibody was raised against a peptide in the C-terminal region of human SMC3.
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亚型
- IgG
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anti-Structural Maintenance of Chromosomes 3 (SMC3) (AA 994-1181) antibody
SMC3 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Structural Maintenance of Chromosomes 3 (SMC3) (C-Term) antibodySMC3 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Structural Maintenance of Chromosomes 3 (SMC3) (AA 1-1217) antibodySMC3 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Structural Maintenance of Chromosomes 3 (SMC3) (AA 711-810) antibodySMC3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2F11 unconjugated
anti-Structural Maintenance of Chromosomes 3 (SMC3) (AA 1178-1216), (C-Term) antibodySMC3 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Structural Maintenance of Chromosomes 3 (SMC3) (AA 1051-1100) antibodySMC3 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 兔, 斑马鱼, 豚鼠, 非洲爪蟾, Bat, 猴, Pig WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Structural Maintenance of Chromosomes 3 (SMC3) (AA 1-1217) antibodySMC3 适用: 人 IP 宿主: 兔 Polyclonal unconjugated
anti-Structural Maintenance of Chromosomes 3 (SMC3) (AA 215-264) antibodySMC3 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 兔, 小鸡, 斑马鱼, 豚鼠, 非洲爪蟾, Bat, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Structural Maintenance of Chromosomes 3 (SMC3) (N-Term) antibodySMC3 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 兔, 斑马鱼, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Structural Maintenance of Chromosomes 3 (SMC3) (C-Term) antibodySMC3 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 兔, 斑马鱼, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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缓冲液
- Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
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- SMC3 (Structural Maintenance of Chromosomes 3 (SMC3))
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别名
- SMC3
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分子量
- 150 kDa
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NCBI登录号
- NP_005436
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途径
- Stem Cell Maintenance
抗原
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