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SATB2 抗体 (C-Term)

This anti-SATB2 antibody is a 兔 多克隆 antibody detecting SATB2 in WB. Suitable for 人.
产品编号 ABIN6972697
发货至: 中国

Quick Overview for SATB2 抗体 (C-Term) (ABIN6972697)

抗原

See all SATB2 抗体
SATB2 (SATB Homeobox 2 (SATB2))

适用

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宿主

  • 55
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克隆类型

  • 41
  • 22
多克隆

标记

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This SATB2 antibody is un-conjugated

应用范围

  • 43
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Western Blotting (WB)
  • 抗原表位

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    C-Term

    产品特性

    SATB2 (SATB homeobox 2, Special AT-Rich Sequence-Binding Protein 2) binds to DNA, at nuclear matrix- or scaffold-associated regions. Thought to recognize the sugar-phosphate structure of double-stranded DNA. Transcription factor controlling nuclear gene expression, by binding to matrix attachment regions (MARs) of DNA and inducing a local chromatin-loop remodeling. Acts as a docking site for several chromatin remodeling enzymes and also by recruiting corepressors (HDACs) or coactivators (HATs) directly to promoters and enhancers. Required for the initiation of the upper-layer neurons (UL1) specific genetic program and for the inactivation of deep-layer neurons (DL) and UL2 specific genes, probably by modulating BCL11B expression. Repressor of Ctip2 and regulatory determinant of corticocortical connections in the developing cerebral cortex. May play an important role in palate formation. Acts as a molecular node in a transcriptional network regulating skeletal development and osteoblast differentiation. SATB2 antibody (pAb) was raised in a Rabbit host. It has been validated for use in Western blot, it has been shown to react with Human samples.

    纯化方法

    Affinity Purified

    免疫原

    This antibody was raised against a peptide within the C-terminal region of human SATB2.

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 缓冲液

    Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
  • 抗原

    SATB2 (SATB Homeobox 2 (SATB2))

    别名

    SATB2

    分子量

    90 kDa

    NCBI登录号

    NP_056080
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