RING1 抗体 (C-Term)
Quick Overview for RING1 抗体 (C-Term) (ABIN6972601)
抗原
See all RING1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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产品特性
- RING1 (Ring Finger Protein 1) constitutes one of the E3 ubiquitin-protein ligases that mediate monoubiquitination of 'Lys-119' of histone H2A, thereby playing a central role in histone code and gene regulation. H2A 'Lys-119' ubiquitination gives a specific tag for epigenetic transcriptional repression and participates in X chromosome inactivation of female mammals. Essential component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, rendering chromatin heritably changed in its expressibility. Compared to RNF2/RING2, it does not have the main E3 ubiquitin ligase activity on histone H2A, and it may rather act as a modulator of RNF2/RING2 activity. RING1 antibody (pAb) was raised in a Rabbit host. It has been validated for use in Western blot, it has been shown to react with Human samples.
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纯化方法
- Affinity Purified
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免疫原
- This antibody was raised against a peptide within the C-terminal region of human RING1.
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亚型
- IgG
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anti-Ring Finger Protein 1 (RING1) (AA 79-263) antibody
RING1 适用: 人 WB, ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 8C12F4 unconjugated
anti-Ring Finger Protein 1 (RING1) antibodyRING1 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Ring Finger Protein 1 (RING1) (AA 79-263) antibodyRING1 适用: 人 ELISA, ICC 宿主: 小鼠 Monoclonal 8E8A2 unconjugated
anti-Ring Finger Protein 1 (RING1) (AA 81-170) antibodyRING1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2B3 unconjugated
anti-Ring Finger Protein 1 (RING1) (AA 81-170) antibodyRING1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4E8 unconjugated
anti-Ring Finger Protein 1 (RING1) (AA 401-630) antibodyRING1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ring Finger Protein 1 (RING1) antibodyRING1 适用: 人 WB, IHC, IP 宿主: 兔 Monoclonal unconjugated
anti-Ring Finger Protein 1 (RING1) (AA 81-170) antibodyRING1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Ring Finger Protein 1 (RING1) antibodyRING1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Ring Finger Protein 1 (RING1) (AA 81-170) antibodyRING1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2A6 unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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缓冲液
- Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
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- RING1 (Ring Finger Protein 1 (RING1))
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别名
- RING1
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分子量
- 50 kDa
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NCBI登录号
- NP_002922
抗原
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