N6-Methyladenosine 抗体
This anti- antibody is a 小鼠 单克隆 antibody detecting in DB 和 IP. Suitable for 人 和 Saccharomyces cerevisiae.
Quick Overview for N6-Methyladenosine 抗体 (ABIN6972397)
抗原
N6-Methyladenosine
适用
人, Saccharomyces cerevisiae
宿主
小鼠
克隆类型
单克隆
标记
非结合性
应用范围
Dot Blot (DB), Immunoprecipitation (IP)
克隆位点
17-3-4-1
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产品特性
- N6-Methyladenosine (m6A) ) is an RNA modification on the N-6 position of adenosine. This modification has been found to be abundant in the 3' UTR and stop codons of mammalian mRNA. m6A is associated with miRNA binding sites suggesting a potential role in epigenetic gene regulation. FTO and ALKBH are demethylases for 6-methyladenosine while a multiprotein complex that includes METTL3 functions as the methyltransferase. Recent findings revealed that m6A is also present on metazoan DNA, suggesting a genuine epigenetic role for this modification in the context of DNA as well. N6-Methyladenosine (m6A) antibody (mAb) (Clone 17-3-4-1) was raised in a Mouse host. It has been validated for use in Dot blot and Immunoprecipitation, it has been shown to react with Budding Yeast and Human samples, but the sequence is not species specific so it should react with a wide range of sample types.
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纯化方法
- Protein A Chromatography
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免疫原
- This antibody was raised against 6-Methyladenosine conjugated to BSA.
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亚型
- IgG1 kappa
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anti-N6-Methyladenosine antibody
适用: 化学剂 DB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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缓冲液
- Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
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- N6-Methyladenosine
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别名
- N6-Methyladenosine (m6A)
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物质类
- Chemical
抗原
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