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IRF4 抗体 (C-Term)

This 兔 多克隆 anti-IRF4 antibody specifically detects IRF4 in WB. The antibody is reactive with 人 samples.
产品编号 ABIN6972213
发货至: 中国
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Quick Overview for IRF4 抗体 (C-Term) (ABIN6972213)

抗原

See all IRF4 抗体
IRF4 (Interferon Regulatory Factor 4 (IRF4))

适用

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宿主

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克隆类型

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多克隆

标记

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This IRF4 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    C-Term

    产品特性

    IRF-4 (Interferon Regulatory Factor 4) is a transcriptional activator. Binds to the interferon-stimulated response element (ISRE) of the MHC class I promoter. Binds the immunoglobulin lambda light chain enhancer, together with PU.1. Probably plays a role in ISRE-targeted signal transduction mechanisms specific to lymphoid cells. Involved in CD8(+) dendritic cell differentiation by forming a complex with the BATF-JUNB heterodimer in immune cells, leading to recognition of AICE sequence (5'-TGAnTCA/GAAA-3'), an immune-specific regulatory element, followed by cooperative binding of BATF and IRF4 and activation of genes (By similarity). IRF-4 antibody (pAb) was raised in a Rabbit host. It has been validated for use in Western blot, it has been shown to react with Human samples.

    纯化方法

    Affinity Purified

    免疫原

    This antibody was raised against a peptide within the C-terminal region of human IRF-4.

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 缓冲液

    Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
  • 抗原

    IRF4 (Interferon Regulatory Factor 4 (IRF4))

    别名

    IRF-4

    分子量

    52 kDa

    NCBI登录号

    NP_002451

    途径

    Chromatin Binding
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