IRF2 抗体 (C-Term)
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北京 101111
Quick Overview for IRF2 抗体 (C-Term) (ABIN6972209)
抗原
See all IRF2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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产品特性
- IRF-2 (interferon regulatory factor 2) specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS)) and represses those genes. Also acts as an activator for several genes including H4 and IL7. Constitutively binds to the ISRE promoter to activate IL7. Involved in cell cycle regulation through binding the site II (HiNF-M) promoter region of H4 and activating transcription during cell growth. Antagonizes IRF1 transcriptional activation. IRF-2 antibody (pAb) was raised in a Rabbit host. It has been validated for use in Western blot, it has been shown to react with Human samples.
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纯化方法
- Affinity Purified
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免疫原
- This IRF-2 antibody was raised against a peptide within the C-terminal region of human IRF-2.
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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缓冲液
- Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
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- IRF2 (Interferon Regulatory Factor 2 (IRF2))
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别名
- IRF-2
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分子量
- 39 kDa
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NCBI登录号
- NP_002190
抗原
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