GLYR1 抗体 (C-Term)
Quick Overview for GLYR1 抗体 (C-Term) (ABIN6971688)
抗原
See all GLYR1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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产品特性
- GLYR1 / NDF (nucleosome-destabilizing factor) that is recruited to gene bodies during transcriptional activation and facilitates Pol II transcription through nucleosomes, where it is proposed to ""unzip"" chromatin during transcription, pushing the polymerase past pause points. It was discovered as a factor that allows p300 to acetylate Histone H3K56, which is normally an inaccessible residue for this modification. GLYR1 is shown to associate with a subset of highly transcribed genes tending to have longer mRNAs rather than shorter, and is also at a significant subset of loci containing the Histone H3K36me3. GLYR1 is expressed at high levels in most tissue types, including stem cells, and has been found to be overexpressed in breast cancer. GLYR1 antibody (pAb) was raised in a Rabbit host. It has been validated for use in Western blot, it has been shown to react with Human samples.
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纯化方法
- Affinity Purified
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免疫原
- This antibody was raised against a peptide within the C-terminal region of human GLYR1.
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亚型
- IgG
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anti-Glyoxylate Reductase 1 Homolog (GLYR1) (AA 1-484) antibody
GLYR1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Glyoxylate Reductase 1 Homolog (GLYR1) antibodyGLYR1 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Glyoxylate Reductase 1 Homolog (GLYR1) antibodyGLYR1 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Glyoxylate Reductase 1 Homolog (GLYR1) (AA 70-270) antibodyGLYR1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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缓冲液
- Purified IgG in 70 mM Tris, 105 mM NaCl, 0.07 mM EDTA, 31 mM glycine, 30 % glycerol, and 0.035 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
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- GLYR1 (Glyoxylate Reductase 1 Homolog (GLYR1))
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别名
- GLYR1
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分子量
- 65 kDa
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NCBI登录号
- NP_115958
抗原
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