FTO 抗体 (N-Term)
Quick Overview for FTO 抗体 (N-Term) (ABIN6971672)
抗原
See all FTO 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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产品特性
- FTO (fat mass and obesity associated) is a dioxygenase that repairs alkylated DNA and RNA by oxidative demethylation. This protein has high activity towards single-stranded RNA containing 3-methyluracil and single-stranded DNA containing 3-methylthymine. FTO has low demethylase activity towards single-stranded DNA containing 1-methyladenine or 3-methylcytosine and has no activity towards 1-methylguanine or double-stranded DNA. FTO contributes to the regulation of the global metabolic rate, energy expenditure, energy homeostasis, regulation of body size and body fat accumulation. FTO has recently been shown to have the highest activity towards demethylation of 6-methyladeninine in single-stranded RNA suggesting that FTO is involved in processing of nuclear RNAs and may play an important role in RNA epigenetics. FTO antibody (pAb) was raised in a Rabbit host. It has been validated for use in Western blot, it has been shown to react with Human samples.
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纯化方法
- Affinity Purified
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免疫原
- This antibody was raised against a peptide within the N-terminal region of human FTO.
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亚型
- IgG
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anti-Fat Mass and Obesity-Associated (FTO) antibody
FTO 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Monoclonal 4G9 unconjugated Recombinant Antibody
anti-Fat Mass and Obesity-Associated (FTO) antibodyFTO 适用: 小鼠 WB, ELISA, IHC, IP 宿主: 小鼠 Monoclonal FT62-6 unconjugated
anti-Fat Mass and Obesity-Associated (FTO) antibodyFTO 适用: 人 WB, ELISA, IHC, IP 宿主: 小鼠 Monoclonal AG103 unconjugated
anti-Fat Mass and Obesity-Associated (FTO) antibodyFTO 适用: 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Fat Mass and Obesity-Associated (FTO) antibodyFTO 适用: 人, 小鼠, 大鼠, 犬, Cow, 绵羊, 马, 灵长类 WB, IHC, IHC (p), IF 宿主: 小鼠 Monoclonal 5-2H10 unconjugated
anti-Fat Mass and Obesity-Associated (FTO) antibodyFTO 适用: 人, 小鼠, 大鼠 WB, ELISA, IP 宿主: 小鼠 Monoclonal FT86-4 unconjugated
anti-Fat Mass and Obesity-Associated (FTO) (AA 416-505) antibodyFTO 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Fat Mass and Obesity-Associated (FTO) (N-Term) antibodyFTO 适用: 人 WB, IF 宿主: 小鼠 Monoclonal 5-2H10 unconjugated
anti-Fat Mass and Obesity-Associated (FTO) (AA 1-30), (N-Term) antibodyFTO 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB21572 unconjugated
anti-Fat Mass and Obesity-Associated (FTO) antibodyFTO 适用: 人 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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缓冲液
- Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
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- FTO (Fat Mass and Obesity-Associated (FTO))
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别名
- FTO
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分子量
- 60 kDa
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NCBI登录号
- NP_001073901
抗原
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