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FOXL2 抗体 (N-Term)

This 兔 多克隆 anti-FOXL2 antibody specifically detects FOXL2 in WB. The antibody is reactive with 人 samples.
产品编号 ABIN6971660
发货至: 中国
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Quick Overview for FOXL2 抗体 (N-Term) (ABIN6971660)

抗原

See all FOXL2 抗体
FOXL2 (Forkhead Box L2 (FOXL2))

适用

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宿主

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克隆类型

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多克隆

标记

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This FOXL2 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    N-Term

    产品特性

    FOXL2 (forkhead box L2, BPES, PFRK, POF3, BPES1, PINTO) is a transcriptional regulator. Critical factor essential for ovary differentiation and maintenance, and repression of the genetic program for somatic testis determination. Prevents trans-differentiation of ovary to testis through transcriptional repression of the Sertoli cell-promoting gene SOX9 (By similarity). Has apoptotic activity in ovarian cells. Suppresses ESR1-mediated transcription of PTGS2/COX2 stimulated by tamoxifen (By similarity). Is a regulator of CYP19 expression (By similarity). Participates in SMAD3-dependent transcription of FST via the intronic SMAD-binding element (By similarity). Is a transcriptional repressor of STAR. Activates SIRT1 transcription under cellular stress conditions. Activates transcription of OSR2. FOXL2 antibody (pAb) was raised in a Rabbit host. It has been validated for use in Western blot, it has been shown to react with Human samples.

    纯化方法

    Affinity Purified

    免疫原

    This FOXL2 antibody was raised against a peptide within the N-terminal region of human FOXL2.

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 缓冲液

    Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
  • 抗原

    FOXL2 (Forkhead Box L2 (FOXL2))

    别名

    FOXL2

    分子量

    40 kDa

    NCBI登录号

    NP_075555

    途径

    Nuclear Hormone Receptor Binding, Positive Regulation of Endopeptidase Activity
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