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BUB1 抗体 (AA 281-419)

BUB1 适用: 人, 小鼠 IF, ICC 宿主: 小鼠 Monoclonal 14H5 unconjugated
产品编号 ABIN6971474
发货至: 中国
  • 抗原 See all BUB1 抗体
    BUB1 (Budding Uninhibited By Benzimidazoles 1 Homolog (Yeast) (BUB1))
    抗原表位
    • 15
    • 8
    • 6
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 281-419
    适用
    • 63
    • 26
    • 7
    • 1
    人, 小鼠
    宿主
    • 56
    • 8
    小鼠
    克隆类型
    • 56
    • 8
    单克隆
    标记
    • 41
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This BUB1 antibody is un-conjugated
    应用范围
    • 55
    • 32
    • 18
    • 13
    • 13
    • 11
    • 10
    • 6
    • 5
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    Immunofluorescence (IF), Immunocytochemistry (ICC)
    产品特性
    Bub1 is a serine-threonine protein kinase and an important regulator of cell division. It is essential for the G2/M mitotic spindle assembly/integrity checkpoint as well as critical for chromosome alignment. Bub1 is required for the assembly of a large number of proteins at the kinetochore, including CENP-E, CENP-F, BUB1B, MAD2L1 and PLK1. It plays a role in sister chromatid cohesion and it serves as a substrate for the anaphase-promoting complex. Bub1 mediates cell death in response to chromosome mis-segregation and acts to suppress spontaneous tumorigenesis. Bub1 antibody (mAb) (Clone 14H5) was raised in a Mouse host. It has been validated for use in Immunocytochemistry and Immunofluorescence, it has been shown to react with Human and Mouse samples.
    纯化方法
    Protein G Chromatography
    免疫原
    This Bub1 antibody was raised against a recombinant protein corresponding to amino acids 281-419 of human Bub1.
    克隆位点
    14H5
    亚型
    IgG
    Top Product
    Discover our top product BUB1 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 缓冲液
    Purified IgG in 70 mM Tris ( pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30 % glycerol and 0.035 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
  • 抗原
    BUB1 (Budding Uninhibited By Benzimidazoles 1 Homolog (Yeast) (BUB1))
    别名
    Bub1 (BUB1 产品)
    别名
    bub1a antibody, bub1l antibody, hbub1 antibody, xbub1 antibody, BUB1A antibody, BUB1L antibody, hBUB1 antibody, AL022991 antibody, Bub1a antibody, C80208 antibody, D2Xrf87 antibody, BUB1 mitotic checkpoint serine/threonine kinase antibody, BUB1, mitotic checkpoint serine/threonine kinase antibody, BUB1 antibody, bub1 antibody, Bub1 antibody
    分子量
    130 kDa
    NCBI登录号
    NP_004327
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