BCL11A 抗体 (AA 637-835)
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北京 101111
Quick Overview for BCL11A 抗体 (AA 637-835) (ABIN6971429)
抗原
See all BCL11A 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 637-835
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产品特性
- BCL11A (B-cell CLL/lymphoma 11A) is a transcriptional regulator, a myeloid and B-cell proto-oncogene and plays important roles in leukemogenesis and hematopoiesis. BCL11A is involved in regulating hemoglobin gene expression. BCL11A regulates hemoglobin gene switching during fetal development and silencing of g-globin expression in adults. BCL11A interacts with the Mi-2/NuRD chromatin remodeling complexes, as well as the erythroid transcription factors GATA1 and FOG1. Abundant expression of full-length forms of BCL11A is developmentally restricted to adult erythroid cells. BCL11A antibody (mAb) (Clone BCL11A/123) was raised in a Mouse host. It has been validated for use in Immunocytochemistry, Immunofluorescence, Immunohistochemistry and Western blot, it has been shown to react with Human samples.
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纯化方法
- Protein G Chromatography
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免疫原
- This BCL11A antibody was raised against a recombinant protein corresponding to amino acids 637-835 of BCL11A-XL (B-cell lymphoma/leukemia 11A extra long form).
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亚型
- IgG1
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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缓冲液
- Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
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- BCL11A (B-Cell CLL/lymphoma 11A (Zinc Finger Protein) (BCL11A))
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别名
- BCL11A
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分子量
- 100 kDa
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NCBI登录号
- NP_075044
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途径
- Regulation of Cell Size
抗原
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