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BCL11A 抗体 (AA 637-835)

This anti-BCL11A antibody is a 小鼠 单克隆 antibody detecting BCL11A in WB, IHC, ICC 和 IF. Suitable for 人.
产品编号 ABIN6971429
发货至: 中国

Quick Overview for BCL11A 抗体 (AA 637-835) (ABIN6971429)

抗原

See all BCL11A 抗体
BCL11A (B-Cell CLL/lymphoma 11A (Zinc Finger Protein) (BCL11A))

适用

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宿主

  • 70
  • 9
小鼠

克隆类型

  • 60
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单克隆

标记

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This BCL11A antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)

克隆位点

BCL11A-123
  • 抗原表位

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    AA 637-835

    产品特性

    BCL11A (B-cell CLL/lymphoma 11A) is a transcriptional regulator, a myeloid and B-cell proto-oncogene and plays important roles in leukemogenesis and hematopoiesis. BCL11A is involved in regulating hemoglobin gene expression. BCL11A regulates hemoglobin gene switching during fetal development and silencing of g-globin expression in adults. BCL11A interacts with the Mi-2/NuRD chromatin remodeling complexes, as well as the erythroid transcription factors GATA1 and FOG1. Abundant expression of full-length forms of BCL11A is developmentally restricted to adult erythroid cells. BCL11A antibody (mAb) (Clone BCL11A/123) was raised in a Mouse host. It has been validated for use in Immunocytochemistry, Immunofluorescence, Immunohistochemistry and Western blot, it has been shown to react with Human samples.

    纯化方法

    Protein G Chromatography

    免疫原

    This BCL11A antibody was raised against a recombinant protein corresponding to amino acids 637-835 of BCL11A-XL (B-cell lymphoma/leukemia 11A extra long form).

    亚型

    IgG1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 缓冲液

    Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
  • 抗原

    BCL11A (B-Cell CLL/lymphoma 11A (Zinc Finger Protein) (BCL11A))

    别名

    BCL11A

    分子量

    100 kDa

    NCBI登录号

    NP_075044

    途径

    Regulation of Cell Size
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