ATRX 抗体 (C-Term)
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北京 101111
Quick Overview for ATRX 抗体 (C-Term) (ABIN6971417)
抗原
See all ATRX 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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产品特性
- ATRX (alpha thalassemia/mental retardation syndrome X-linked protein, X-linked helicase II, XNP) is a transcriptional regulator and a member of the SWI/SNF family of chromatin remodeling proteins. It contains an SNF2 domain and helicase domain, and a PHD finger. ATRX undergoes cell cycle-dependent phosphorylation, which regulates its nuclear matrix and chromatin association, and suggests its involvement in interphase gene regulation and chromosomal segregation in mitosis. Mutations of the ATRX gene are associated with an X-linked mental retardation syndrome most often accompanied by alpha-thalassemia (ATRX) syndrome. These mutations have been shown to cause diverse changes in the pattern of DNA methylation, which may provide a link between chromatin remodeling, DNA methylation, and gene expression in developmental processes. ATRX antibody (pAb) was raised in a Rabbit host. It has been validated for use in Western blot, it has been shown to react with Human samples.
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纯化方法
- Affinity Purified
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免疫原
- This ATRX antibody was raised against a peptide within the C-terminus of human ATRX.
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亚型
- IgG
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anti-helicase 2, X-linked (ATRX) (C-Term) antibody
ATRX 适用: 人, 小鼠 WB, IF, IHC (p), ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-helicase 2, X-linked (ATRX) (AA 2161-2443) antibodyATRX 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-helicase 2, X-linked (ATRX) (AA 2311-2492) antibodyATRX 适用: 人 ELISA 宿主: 小鼠 Monoclonal 8B2H9 unconjugated
anti-helicase 2, X-linked (ATRX) antibodyATRX 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-helicase 2, X-linked (ATRX) (N-Term) antibodyATRX 适用: 人, 小鼠 ELISA, IHC, WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-helicase 2, X-linked (ATRX) (AA 2311-2410) antibodyATRX 适用: 人 ELISA, WB, IF 宿主: 小鼠 Monoclonal 5B3 unconjugated
anti-helicase 2, X-linked (ATRX) antibodyATRX 适用: 人 IHC, ISt, StM 宿主: 兔 Monoclonal ATRX-2900R unconjugated Recombinant Antibody
anti-helicase 2, X-linked (ATRX) antibodyATRX 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal 39f unconjugated
anti-helicase 2, X-linked (ATRX) (N-Term) antibodyATRX 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-helicase 2, X-linked (ATRX) antibodyATRX 适用: 人 ELISA, Coat 宿主: 小鼠 Monoclonal 23c unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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缓冲液
- Purified IgG in 70 mM Tris ( pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30 % glycerol and 0.035 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
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- ATRX (helicase 2, X-linked (ATRX))
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别名
- ATRX
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分子量
- 300 kDa
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NCBI登录号
- NP_000480
抗原
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