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ATRX 抗体 (C-Term)

This anti-ATRX antibody is a 兔 多克隆 antibody detecting ATRX in WB. Suitable for 人.
产品编号 ABIN6971417
发货至: 中国

Quick Overview for ATRX 抗体 (C-Term) (ABIN6971417)

抗原

See all ATRX 抗体
ATRX (helicase 2, X-linked (ATRX))

适用

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宿主

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克隆类型

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多克隆

标记

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This ATRX antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    C-Term

    产品特性

    ATRX (alpha thalassemia/mental retardation syndrome X-linked protein, X-linked helicase II, XNP) is a transcriptional regulator and a member of the SWI/SNF family of chromatin remodeling proteins. It contains an SNF2 domain and helicase domain, and a PHD finger. ATRX undergoes cell cycle-dependent phosphorylation, which regulates its nuclear matrix and chromatin association, and suggests its involvement in interphase gene regulation and chromosomal segregation in mitosis. Mutations of the ATRX gene are associated with an X-linked mental retardation syndrome most often accompanied by alpha-thalassemia (ATRX) syndrome. These mutations have been shown to cause diverse changes in the pattern of DNA methylation, which may provide a link between chromatin remodeling, DNA methylation, and gene expression in developmental processes. ATRX antibody (pAb) was raised in a Rabbit host. It has been validated for use in Western blot, it has been shown to react with Human samples.

    纯化方法

    Affinity Purified

    免疫原

    This ATRX antibody was raised against a peptide within the C-terminus of human ATRX.

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 缓冲液

    Purified IgG in 70 mM Tris ( pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30 % glycerol and 0.035 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
  • 抗原

    ATRX (helicase 2, X-linked (ATRX))

    别名

    ATRX

    分子量

    300 kDa

    NCBI登录号

    NP_000480
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