ATAD2 抗体 (C-Term)
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Quick Overview for ATAD2 抗体 (C-Term) (ABIN6971405)
抗原
See all ATAD2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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产品特性
- ATAD2 (ATPase family AAA domain-containing protein 2) may be a transcriptional coactivator of the nuclear receptor ESR1 required to induce the expression of a subset of estradiol target genes, such as CCND1, MYC and E2F1. May play a role in the recruitment or occupancy of CREBBP at some ESR1 target gene promoters. May be required for histone hyperacetylation. Involved in the estrogen-induced cell proliferation and cell cycle progression of breast cancer cells. ATAD2 antibody (pAb) was raised in a Rabbit host. It has been validated for use in Immunoprecipitation and Western blot, it has been shown to react with Human samples.
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纯化方法
- Affinity Purified
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免疫原
- This antibody was raised against a peptide within the C-terminal region of human ATAD2.
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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缓冲液
- Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
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- ATAD2 (ATPase Family, AAA Domain Containing 2 (ATAD2))
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别名
- ATAD2
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分子量
- 160 kDa
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NCBI登录号
- NP_054828
抗原
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