NCOA3 抗体
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北京 101111
Quick Overview for NCOA3 抗体 (ABIN6971371)
抗原
See all NCOA3 抗体适用
宿主
克隆类型
标记
应用范围
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产品特性
- AIB1 (Amplified in Breast Cancer 1, Steroid Receptor Coactivator-3, Nuclear Receptor Coactivator 3, SRC-3, NCOA3) is a chromatin-associated protein that interacts with nuclear hormone receptors to modify their activity as transcriptional activators. AIB1 has histone acetyltransferase (HAT) activity and recruits p300/CBP-associated factor (PCAF) and CREB binding protein (CBP) as part of a multisubunit co-activator complex. This protein is initially found in the cytoplasm but is translocated into the nucleus upon phosphorylation. It is Involved in the coactivation of different nuclear receptors, such as GR, ER, RARs, RXRs, TRs, VDR and PPARs. It is also involved in the coactivation of the NF-kappa-B pathway via its interaction with the NFkB1 protein. AIB1 / SRC-3 antibody (pAb) was raised in a Rabbit host. It has been validated for use in Chromatin Immunoprecipitation and Western blot, it has been shown to react with Human samples.
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纯化方法
- Affinity Purified
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免疫原
- This AIB1 antibody was raised against a peptide derived from human AIB1/SRC-3.
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亚型
- IgG
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anti-Nuclear Receptor Coactivator 3 (NCOA3) (AA 1023-1304) antibody
NCOA3 适用: 人 WB, ELISA, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Coactivator 3 (NCOA3) antibodyNCOA3 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Coactivator 3 (NCOA3) (AA 576-625) antibodyNCOA3 适用: 人, Cow, Pig, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Coactivator 3 (NCOA3) (AA 188-198) antibodyNCOA3 适用: 人, Cow, 犬, Pig, 猴, Bat, Hamster IHC, IHC (p) 宿主: 山羊 Polyclonal unconjugated
anti-Nuclear Receptor Coactivator 3 (NCOA3) (Internal Region) antibodyNCOA3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Coactivator 3 (NCOA3) antibodyNCOA3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 5H3 unconjugated
anti-Nuclear Receptor Coactivator 3 (NCOA3) (pThr24) antibodyNCOA3 适用: 人 ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Coactivator 3 (NCOA3) (AA 344-372), (N-Term) antibodyNCOA3 适用: 人 WB 宿主: 兔 Polyclonal RB41497 unconjugated
anti-Nuclear Receptor Coactivator 3 (NCOA3) (AA 1-200) antibodyNCOA3 适用: 人 ELISA 宿主: 小鼠 Monoclonal 2C11B12 unconjugated
anti-Nuclear Receptor Coactivator 3 (NCOA3) (Middle Region) antibodyNCOA3 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, Pig WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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缓冲液
- Purified IgG in 70 mM Tris ( pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30 % glycerol and 0.035 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
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- NCOA3 (Nuclear Receptor Coactivator 3 (NCOA3))
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别名
- AIB1 / SRC-3
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分子量
- 160 kDa
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NCBI登录号
- NP_858045
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途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Lipid Metabolism by PPARalpha
抗原
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