AGO4 抗体 (AA 1-164)
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北京 101111
Quick Overview for AGO4 抗体 (AA 1-164) (ABIN6971367)
抗原
See all AGO4 (EIF2C4) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-164
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产品特性
- Argonaute 4 (Ago4, aka EIF2C4) is a member of the Argonaute family of proteins involved in RNAi mediated gene silencing through siRNA and miRNA effectors. The Argonaute proteins are part of RISC, the RNAi Induced Silencing Complex. Ago4 lacks RNase activity and does not appear to cleave target mRNA molecules. It binds to microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Ago4 has both a PAZ and a PIWI domain, indicative of the Argonaute family of proteins. Ago4 antibody (mAb) (Clone 1B7-G11) was raised in a Mouse host. It has been validated for use in Immunoprecipitation and Western blot, it has been shown to react with Human samples.
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纯化方法
- Protein G Chromatography
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免疫原
- This Ago4 antibody was raised against a recombinant protein corresponding to amino acids 1-164 of human Ago4.
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亚型
- IgG
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anti-Eukaryotic Translation Initiation Factor 2C, 4 (EIF2C4) (AA 716-861) antibody
EIF2C4 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 2C, 4 (EIF2C4) antibodyEIF2C4 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 2C, 4 (EIF2C4) (AA 1-100) antibodyEIF2C4 适用: 人 ELISA 宿主: 小鼠 Monoclonal 4G3 unconjugated
anti-Eukaryotic Translation Initiation Factor 2C, 4 (EIF2C4) (N-Term) antibodyEIF2C4 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 2C, 4 (EIF2C4) (AA 611-660) antibodyEIF2C4 适用: 人, 大鼠, 犬, 豚鼠, 兔, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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缓冲液
- Purified IgG in 70 mM Tris ( pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30 % glycerol and 0.035 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
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- AGO4 (EIF2C4) (Eukaryotic Translation Initiation Factor 2C, 4 (EIF2C4))
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别名
- Ago4
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分子量
- 100 kDa
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NCBI登录号
- NP_060099
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途径
- Fc-epsilon Receptor Signaling Pathway, Regulatory RNA Pathways, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Cellular Glucan Metabolic Process
抗原
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