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IL-31 抗体

This anti-IL-31 antibody is a 小鼠 单克隆 antibody detecting IL-31 in Neut. Suitable for 人.
产品编号 ABIN6964030
发货至: 中国

Quick Overview for IL-31 抗体 (ABIN6964030)

抗原

See all IL-31 (IL31) 抗体
IL-31 (IL31) (Interleukin 31 (IL31))

适用

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宿主

  • 74
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小鼠

克隆类型

  • 68
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单克隆

标记

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This IL-31 antibody is un-conjugated

应用范围

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Neutralization (Neut)

克隆位点

MT313
  • 特异性

    Native and recombinant human IL-31

    纯化方法

    Purified from in vitro cultures by protein G affinity chromatography.

    免疫原

    Recombinant human IL-31

    亚型

    IgG1
  • 应用备注

    Neutralization of human IL-31 bioactivity. It is recommended to establish the optimal antibody concentration for the assay system used. Neutralization Neutralization assay: Neutralization of human IL-31 induced IL-6 production (see graph). To determine the neutralizing capacity and ND50, mixtures of human recombinant IL-31 (50 ng/ ml) and various concentrations of mAb MT313 were added to human aortic endothelial cells that had been pre-stimulated with recombinant human IFN-γ (10 ng/mL). Following overnight incubation, cell supernatants were quantified in IL-6 ELISA. Neutralization dose 50 (ND50): MT313 neutralized the effect of human IL-31 at a ND50value of 0.1-0.6 μg/mL when 50 ng/mL of human IL-31 was present. ND50 is defined as the concentration of antibody that results in 50 % inhibition of the biological response under the experimental conditions specified.

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    supplied at 1 mg/mL in PBS free of preservatives

    储存液

    Without preservative

    储存条件

    4 °C,-20 °C

    储存方法

    Store product at 4-8°C or frozen at -20°C or below. Avoid repeated freezing/thawing.

    有效期

    18 months
  • 抗原

    IL-31 (IL31) (Interleukin 31 (IL31))

    别名

    IL31

    基因ID

    386653
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