IL23 抗体
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北京 101111
Quick Overview for IL23 抗体 (ABIN6964023)
抗原
See all IL23 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Native and recombinant IL-23. The antibody recognizes the p19 subunit of the IL-23 heterodimer (p40+p19).
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纯化方法
- Purified from in vitro cultures by protein G affinity chromatography.
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免疫原
- Recombinant human IL-23
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亚型
- IgG2b
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anti-Interleukin 23 (IL23) (AA 101-196) antibody
IL23 适用: 人, 大鼠 WB, ELISA, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 23 (IL23) antibodyIL23 适用: 人 IHC, ELISA, Func 宿主: 小鼠 Monoclonal B-Z23 unconjugated
anti-Interleukin 23 (IL23) (C-Term) antibodyIL23 适用: 人, 小鼠 WB, ELISA, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Neutralization of human IL-23 bioactivity. It is recommended to establish the optimal antibody concentration for the assay system used. The antibody is also suitable for immunoassays. Neutralization Neutralization assay: Neutralization of human IL-23 induced IFN-γ production (see graph). To determine the neutralizing capacity and ND50, mixtures of various concentrations of mAb MT155, human recombinant IL-23 (10 ng/mL) and recombinant human IL-18 (50 ng/mL) were added to human PBMC. Following overnight incubation, cell supernatants were quantified in IFN-γ ELISA. Neutralization dose 50 (ND50): MT155 neutralized the effect of IL-23 at a ND50value of 0.2-0.8 μg/mL when 10 ng/mL recombinant human IL-23 was present. ND50 is defined as the concentration of antibody that results in 50 % inhibition of the biological response under the experimental conditions specified.
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- supplied at 1 mg/mL in PBS free of preservatives
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储存液
- Without preservative
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储存条件
- 4 °C,-20 °C
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储存方法
- Store product at 4-8°C or frozen at -20°C or below. Avoid repeated freezing/thawing.
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有效期
- 18 months
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- IL23 (Interleukin 23 (IL23))
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别名
- IL23
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基因ID
- 51561
抗原
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