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IL-4 抗体

Cited in 3+ publications. This 大鼠 单克隆 anti-IL-4 antibody (Clone 11B11) specifically detects IL-4 in Neut. The antibody is reactive with 小鼠 samples.
产品编号 ABIN6964013
发货至: 中国
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中国
北京 101111
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Room 801-803
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Quick Overview for IL-4 抗体 (ABIN6964013)

抗原

See all IL-4 (IL4) 抗体
IL-4 (IL4) (Interleukin 4 (IL4))

适用

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小鼠

宿主

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大鼠

克隆类型

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单克隆

标记

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This IL-4 antibody is un-conjugated

应用范围

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Neutralization (Neut)

克隆位点

11B11
  • 特异性

    Native and recombinant mouse IL-4

    纯化方法

    Purified from in vitro cultures by protein G affinity chromatography.

    免疫原

    Recombinant mouse IL-4

    亚型

    IgG1
  • 应用备注

    Neutralization of mouse IL-4 bioactivity. It is recommended to establish the optimal antibody concentration for the assay system used. The antibody is also suitable for immunoassays.

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    supplied at 1 mg/mL in PBS free of preservatives

    储存液

    Without preservative

    储存条件

    4 °C,-20 °C

    储存方法

    Store product at 4-8°C or frozen at -20°C or below. Avoid repeated freezing/ thawing.

    有效期

    18 months
  • Cavassani, Tristao, Oliveira, Rocha, Vancim, Moreira, Campanelli, Panagio, Milanezi, Martinez, Rossi, Silva: "Cell-free antigens from Paracoccidioides brasiliensis drive IL-4 production and increase the severity of paracoccidioidomycosis." in: PLoS ONE, Vol. 6, Issue 6, pp. e21423, (2011) (PubMed).

    Costa, Carregaro, Lima-Júnior, Silva, Milanezi, Cardoso, Giudice, de Jesus, Carvalho, Almeida, Silva: "BALB/c mice infected with antimony treatment refractory isolate of Leishmania braziliensis present severe lesions due to IL-4 production." in: PLoS neglected tropical diseases, Vol. 5, Issue 3, pp. e965, (2011) (PubMed).

    Iizuka, Ikarashi, Yoshida, Heike, Takeda, Quinn, Wakasugi, Kitagawa, Takaue: "Interleukin (IL)-4 promotes T helper type 2-biased natural killer T (NKT) cell expansion, which is regulated by NKT cell-derived interferon-gamma and IL-4." in: Immunology, Vol. 123, Issue 1, pp. 100-7, (2008) (PubMed).

  • 抗原

    IL-4 (IL4) (Interleukin 4 (IL4))

    别名

    IL4

    基因ID

    16189

    途径

    JAK/STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport, Activated T Cell Proliferation
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