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APOE 抗体 (Biotin)

This anti-APOE antibody is a 大鼠 单克隆 antibody detecting APOE in WB 和 ELISA. Suitable for 小鼠. This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN6963955
发货至: 中国

Quick Overview for APOE 抗体 (Biotin) (ABIN6963955)

抗原

See all APOE 抗体
APOE (Apolipoprotein E (APOE))

适用

  • 111
  • 85
  • 74
  • 4
  • 4
  • 2
  • 2
  • 1
  • 1
  • 1
小鼠

宿主

  • 124
  • 46
  • 9
  • 1
  • 1
大鼠

克隆类型

  • 122
  • 58
单克隆

标记

  • 98
  • 17
  • 11
  • 6
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
This APOE antibody is conjugated to Biotin

应用范围

  • 145
  • 69
  • 60
  • 47
  • 44
  • 39
  • 39
  • 22
  • 13
  • 12
  • 9
  • 6
  • 5
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), ELISA

克隆位点

ME29
  • 特异性

    Apolipoprotein E

    纯化方法

    Purified from in vitro cultures by protein G affinity chromatography.

    免疫原

    Recombinant mouse apoE

    亚型

    IgG2a
  • 应用备注

    For quantification of mouse apoE in serum/plasma samples and cell culture supernatants using ELISA. mE29 is recommended as detection mAb in combination with coating mAb mE1 . The antibody is also suitable for immunoprecipitation and Western blot.

    说明

    Biotinylated through reaction with a N-hydroxysuccinimide ester of biotin.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5 mg/mL

    缓冲液

    supplied at 0.5 mg/mL in PBS with 0.02 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store product at 4-8°C or frozen at -20°C or below. Avoid repeated freezing/ thawing.

    有效期

    18 months
  • Gordon, Yao, Xu, Karkowsky, Kaler, Kalchiem-Dekel, Barochia, Gao, Keeran, Jeffries, Levine: "Apolipoprotein E is a concentration-dependent pulmonary danger signal that activates the NLRP3 inflammasome and IL-1β secretion by bronchoalveolar fluid macrophages from asthmatic subjects." in: The Journal of allergy and clinical immunology, Vol. 144, Issue 2, pp. 426-441.e3, (2020) (PubMed).

    Centa, Prokopec, Garimella, Habir, Hofste, Stark, Dahdah, Tibbitt, Polyzos, Gisterå, Johansson, Maeda, Hansson, Ketelhuth, Coquet, Binder, Karlsson, Malin: "Acute Loss of Apolipoprotein E Triggers an Autoimmune Response That Accelerates Atherosclerosis." in: Arteriosclerosis, thrombosis, and vascular biology, Vol. 38, Issue 8, pp. e145-e158, (2019) (PubMed).

  • 抗原

    APOE (Apolipoprotein E (APOE))

    别名

    apoE

    基因ID

    11816

    途径

    Regulation of Cell Size, Lipid Metabolism
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