APOB 抗体 (Biotin)
Quick Overview for APOB 抗体 (Biotin) (ABIN6963945)
抗原
See all APOB 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
特异性
- Native apoB in the form of LDL.
-
交叉反应 (详细)
- The monoclonal antibody cross-reacts with apoB from non-human primates.
-
纯化方法
- Purified from in vitro cultures by protein G affinity chromatography.
-
免疫原
- Human LDL
-
亚型
- IgG1
-
-
-
-
应用备注
- For quantification of apoB in serum/plasma samples and cell culture supernatants using ELISA. LDL 11 is recommended as detection mAb in combination with coating mAb LDL 20/17 . The antibody is also suitable for immunoprecipitation and Western blot.
-
说明
-
Biotinylated through reaction with a N-hydroxysuccinimide ester of biotin.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- supplied at 1 mg/mL in PBS with 0.02 % sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Store product at 4-8°C or frozen at -20°C or below. Avoid repeated freezing/ thawing.
-
有效期
- 18 months
-
-
-
GPR146 Deficiency Protects against Hypercholesterolemia and Atherosclerosis." in: Cell, Vol. 179, Issue 6, pp. 1276-1288.e14, (2020) (PubMed).
: "A Drug Screen using Human iPSC-Derived Hepatocyte-like Cells Reveals Cardiac Glycosides as a Potential Treatment for Hypercholesterolemia." in: Cell stem cell, Vol. 20, Issue 4, pp. 478-489.e5, (2017) (PubMed).
: "Synthesis and Characterization of Fatty Acid Conjugates of Niacin and Salicylic Acid." in: Journal of medicinal chemistry, Vol. 59, Issue 3, pp. 1217-31, (2016) (PubMed).
: "Development and rescue of human familial hypercholesterolaemia in a xenograft mouse model." in: Nature communications, Vol. 6, pp. 7339, (2015) (PubMed).
: "Inhibition of bone morphogenetic protein signaling reduces vascular calcification and atherosclerosis." in: Arteriosclerosis, thrombosis, and vascular biology, Vol. 32, Issue 3, pp. 613-22, (2012) (PubMed).
: "
-
GPR146 Deficiency Protects against Hypercholesterolemia and Atherosclerosis." in: Cell, Vol. 179, Issue 6, pp. 1276-1288.e14, (2020) (PubMed).
-
- APOB (Apolipoprotein B (APOB))
-
别名
- apoB
-
基因ID
- 338
-
途径
- Lipid Metabolism
抗原
-