APOE 抗体 (Biotin)
Quick Overview for APOE 抗体 (Biotin) (ABIN6963938)
抗原
See all APOE 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
特异性
- Native and recombinant apolipoprotein E (isoforms apoE2, apoE3 and apoE4).
-
交叉反应 (详细)
- The monoclonal antibody cross-reacts with apoE from non-human primates.
-
纯化方法
- Purified from in vitro cultures by protein G affinity chromatography.
-
免疫原
- Purified human apolipoprotein E
-
亚型
- IgG1
-
-
-
-
应用备注
- For quantification of apoE in serum/plasma samples and cell culture supernatants using ELISA and for enumeration of human apoE producing cells using ELISpot. E887 is recommended as detection mAb in combination with coating mAb E276 . The antibody is also suitable for immunoprecipitation and Western blot.
-
说明
-
Biotinylated through reaction with a N-hydroxysuccinimide ester of biotin.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 0.5 mg/mL
-
缓冲液
- supplied at 0.5 mg/mL in PBS with 0.02 % sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Store product at 4-8°C or frozen at -20°C or below. Avoid repeated freezing/ thawing.
-
有效期
- 18 months
-
-
-
Development and rescue of human familial hypercholesterolaemia in a xenograft mouse model." in: Nature communications, Vol. 6, pp. 7339, (2015) (PubMed).
: "Role of hypervariable region 1 for the interplay of hepatitis C virus with entry factors and lipoproteins." in: Journal of virology, Vol. 88, Issue 21, pp. 12644-55, (2014) (PubMed).
: "ApoE production in human monocytes and its regulation by inflammatory cytokines." in: PLoS ONE, Vol. 8, Issue 11, pp. e79908, (2014) (PubMed).
: "Two apolipoprotein E mimetic peptides with similar cholesterol reducing properties exhibit differential atheroprotective effects in LDL-R null mice." in: Atherosclerosis, Vol. 227, Issue 1, pp. 58-64, (2013) (PubMed).
: "Apolipoprotein E does not cross the blood-cerebrospinal fluid barrier, as revealed by an improved technique for sampling CSF from mice." in: American journal of physiology. Regulatory, integrative and comparative physiology, Vol. 303, Issue 9, pp. R903-8, (2013) (PubMed).
: "
-
Development and rescue of human familial hypercholesterolaemia in a xenograft mouse model." in: Nature communications, Vol. 6, pp. 7339, (2015) (PubMed).
-
- APOE (Apolipoprotein E (APOE))
-
别名
- apoE
-
基因ID
- 348
-
途径
- Regulation of Cell Size, Lipid Metabolism
抗原
-