电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

APOE 抗体 (Biotin)

Cited in 5+ publications. This Biotin-conjugated 小鼠 单克隆 anti-APOE antibody (Clone E887) specifically detects APOE in WB, ELISA 和 ELISpot. The antibody is reactive with 人 和 Non-Human Primate samples.
产品编号 ABIN6963938
发货至: 中国
Contact our Customer Service for availability and price in your country. Contact Info

Our Local Distributor

中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for APOE 抗体 (Biotin) (ABIN6963938)

抗原

See all APOE 抗体
APOE (Apolipoprotein E (APOE))

适用

  • 121
  • 92
  • 59
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
人, Non-Human Primate

宿主

  • 122
  • 32
  • 10
  • 2
  • 1
小鼠

克隆类型

  • 112
  • 54
单克隆

标记

  • 77
  • 18
  • 10
  • 6
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
This APOE antibody is conjugated to Biotin

应用范围

  • 125
  • 57
  • 49
  • 39
  • 39
  • 29
  • 26
  • 21
  • 20
  • 12
  • 7
  • 6
  • 5
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), ELISA, ELISpot

克隆位点

E887
  • 特异性

    Native and recombinant apolipoprotein E (isoforms apoE2, apoE3 and apoE4).

    交叉反应 (详细)

    The monoclonal antibody cross-reacts with apoE from non-human primates.

    纯化方法

    Purified from in vitro cultures by protein G affinity chromatography.

    免疫原

    Purified human apolipoprotein E

    亚型

    IgG1
  • 应用备注

    For quantification of apoE in serum/plasma samples and cell culture supernatants using ELISA and for enumeration of human apoE producing cells using ELISpot. E887 is recommended as detection mAb in combination with coating mAb E276 . The antibody is also suitable for immunoprecipitation and Western blot.

    说明

    Biotinylated through reaction with a N-hydroxysuccinimide ester of biotin.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5 mg/mL

    缓冲液

    supplied at 0.5 mg/mL in PBS with 0.02 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store product at 4-8°C or frozen at -20°C or below. Avoid repeated freezing/ thawing.

    有效期

    18 months
  • Bissig-Choisat, Wang, Legras, Saha, Chen, Bell, Pankowicz, Hill, Barzi, Leyton, Leung, Kruse, Himes, Goss, Wilson, Chan, Lagor, Bissig: "Development and rescue of human familial hypercholesterolaemia in a xenograft mouse model." in: Nature communications, Vol. 6, pp. 7339, (2015) (PubMed).

    Bankwitz, Vieyres, Hueging, Bitzegeio, Doepke, Chhatwal, Haid, Catanese, Zeisel, Nicosia, Baumert, Kaderali, Pietschmann: "Role of hypervariable region 1 for the interplay of hepatitis C virus with entry factors and lipoproteins." in: Journal of virology, Vol. 88, Issue 21, pp. 12644-55, (2014) (PubMed).

    Braesch-Andersen, Paulie, Smedman, Mia, Kumagai-Braesch: "ApoE production in human monocytes and its regulation by inflammatory cytokines." in: PLoS ONE, Vol. 8, Issue 11, pp. e79908, (2014) (PubMed).

    Handattu, Nayyar, Garber, Palgunachari, Monroe, Keenum, Mishra, Datta, Anantharamaiah: "Two apolipoprotein E mimetic peptides with similar cholesterol reducing properties exhibit differential atheroprotective effects in LDL-R null mice." in: Atherosclerosis, Vol. 227, Issue 1, pp. 58-64, (2013) (PubMed).

    Liu, Kuhel, Shen, Hui, Woods: "Apolipoprotein E does not cross the blood-cerebrospinal fluid barrier, as revealed by an improved technique for sampling CSF from mice." in: American journal of physiology. Regulatory, integrative and comparative physiology, Vol. 303, Issue 9, pp. R903-8, (2013) (PubMed).

  • 抗原

    APOE (Apolipoprotein E (APOE))

    别名

    apoE

    基因ID

    348

    途径

    Regulation of Cell Size, Lipid Metabolism
You are here: