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- 抗原 See all APOE 抗体
- APOE (Apolipoprotein E (APOE))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This APOE antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, ELISpot
- 特异性
- Native and recombinant human apolipoprotein E (isoforms apoE2, apoE3 and apoE4).
- 纯化方法
- Purified from in vitro cultures by protein G affinity chromatography.
- 免疫原
- Purified human apolipoprotein E
- 克隆位点
- E276
- 亚型
- IgG1
- Top Product
- Discover our top product APOE Primary Antibody
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- 应用备注
- For quantification of apoE in serum/plasma samples and cell culture supernatants using ELISA and for enumeration of apoE producing cells using ELISpot. E276 is recommended as coating mAb in combination with detection mAb E887 . The antibody is also suitable for immunoprecipitation and Western blot.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.5 mg/mL
- 缓冲液
- supplied at 0.5 mg/mL in PBS with 0.02 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store product at 4-8°C or frozen at -20°C or below. Avoid repeated freezing/ thawing.
- 有效期
- 18 months
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CSF ApoE predicts clinical progression in nondemented APOEε4 carriers." in: Neurobiology of aging, Vol. 57, pp. 186-194, (2018) (PubMed).
: "Development and rescue of human familial hypercholesterolaemia in a xenograft mouse model." in: Nature communications, Vol. 6, pp. 7339, (2015) (PubMed).
: "ApoE production in human monocytes and its regulation by inflammatory cytokines." in: PLoS ONE, Vol. 8, Issue 11, pp. e79908, (2014) (PubMed).
: "Two apolipoprotein E mimetic peptides with similar cholesterol reducing properties exhibit differential atheroprotective effects in LDL-R null mice." in: Atherosclerosis, Vol. 227, Issue 1, pp. 58-64, (2013) (PubMed).
: "Apolipoprotein E does not cross the blood-cerebrospinal fluid barrier, as revealed by an improved technique for sampling CSF from mice." in: American journal of physiology. Regulatory, integrative and comparative physiology, Vol. 303, Issue 9, pp. R903-8, (2013) (PubMed).
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CSF ApoE predicts clinical progression in nondemented APOEε4 carriers." in: Neurobiology of aging, Vol. 57, pp. 186-194, (2018) (PubMed).
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- 抗原
- APOE (Apolipoprotein E (APOE))
- 别名
- apoE (APOE 产品)
- 基因ID
- 348
- 途径
- Regulation of Cell Size, Lipid Metabolism
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