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TXN 抗体 (Biotin)

Cited in 4+ publications. The Biotin-conjugated 小鼠 单克隆 anti-TXN antibody (Clone MT13X3) (ABIN6963928) specifically detects TXN in WB 和 ELISA. The antibody is reactive with 人 samples.
产品编号 ABIN6963928
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Quick Overview for TXN 抗体 (Biotin) (ABIN6963928)

抗原

See all TXN 抗体
TXN (Thioredoxin (TXN))

适用

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宿主

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小鼠

克隆类型

  • 72
  • 61
单克隆

标记

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This TXN antibody is conjugated to Biotin

应用范围

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Western Blotting (WB), ELISA

克隆位点

MT13X3
  • 特异性

    Native and recombinant Thioredoxin-1

    交叉反应 (详细)

    The antibody cross-reacts with Trx1 from cow. For quantification of human Trx1 in ELISA, samples should not contain bovine serum.

    纯化方法

    Purified from in vitro cultures by protein G affinity chromatography.

    免疫原

    Recombinant human Thioredoxin-1

    亚型

    IgG1
  • 应用备注

    For quantification of Trx1 in solution e.g. cell culture supernatants and serum/ plasma using ELISA. MT13X3 is recommended as detection mAb in combination with coating mAb MT17R6 . MT13X3 is also suitable for Western blot.

    说明

    Biotinylated through reaction with a N-hydroxysuccinimide ester of biotin.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5 mg/mL

    缓冲液

    supplied at 0.5 mg/mL in PBS with 0.02 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store product at 4-8°C or frozen at -20°C or below. Avoid repeated freezing/ thawing.

    有效期

    18 months
  • Faghih, Rostami-Nejad, Amani, Sadeghi, Pourhoseingholi, Masotti, Zali: "Analysis of IL17A and IL21 Expression in the Small Intestine of Celiac Disease Patients and Correlation with Circulating Thioredoxin Level." in: Genetic testing and molecular biomarkers, Vol. 22, Issue 9, pp. 518-525, (2018) (PubMed).

    Mahmoudian, Khalilnezhad, Gharagozli, Amani et al.: "Thioredoxin-1, redox factor-1 and thioredoxin-interacting protein, mRNAs are differentially expressed in Multiple Sclerosis patients exposed and non-exposed to interferon and immunosuppressive ..." in: Gene, Vol. 634, pp. 29-36, (2017) (PubMed).

    Reiser, Mathys, Curbo, Pannecouque, Noppen, Liekens, Engman, Lundberg, Balzarini, Karlsson: "The Cellular Thioredoxin-1/Thioredoxin Reductase-1 Driven Oxidoreduction Represents a Chemotherapeutic Target for HIV-1 Entry Inhibition." in: PLoS ONE, Vol. 11, Issue 1, pp. e0147773, (2016) (PubMed).

    Lundberg, Curbo, Reiser, Masterman, Braesch-Andersen, Areström, Ahlborg: "Methodological aspects of ELISA analysis of thioredoxin 1 in human plasma and cerebrospinal fluid." in: PLoS ONE, Vol. 9, Issue 7, pp. e103554, (2015) (PubMed).

  • 抗原

    TXN (Thioredoxin (TXN))

    别名

    Thioredoxin1

    基因ID

    7295

    途径

    Carbohydrate Homeostasis, Cell RedoxHomeostasis
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