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IL12/23 (p40), IL23, IL12 (p70) 抗体

This 小鼠 单克隆 antibody specifically detects IL12/23 (p40), IL23, IL12 (p70) in ELISA 和 ELISpot. It exhibits reactivity toward 人 和 Non-Human Primate. It has been mentioned in 4+ publications
产品编号 ABIN6963860
发货至: 中国
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Quick Overview for IL12/23 (p40), IL23, IL12 (p70) 抗体 (ABIN6963860)

抗原

IL12/23 (p40), IL23, IL12 (p70)

适用

人, Non-Human Primate

宿主

小鼠

克隆类型

单克隆

应用范围

ELISA, ELISpot

克隆位点

MT86-221
  • 特异性

    Native and recombinant p40 subunit of IL-12 and IL-23. The antibodies recognize p40 monomer, p40 homodimer, IL-12 p70 heterodimer (p40+p35) and IL-23 heterodimer (p40+p19).

    交叉反应 (详细)

    The monoclonal antibodies cross-react with the p40 subunit of IL-12 and IL-23 from non-human primates.

    产品特性

    These monoclonal antibodies enable specific detection of the p40 subunit of human IL-12 and IL-23 in immunoassays such as ELISpot, FluoroSpot, and ELISA. Serum/Plasma samples

    纯化方法

    Purified from in vitro cultures by protein G affinity chromatography.

    过滤

    0.2 μm filtered

    免疫原

    Recombinant human IL-23

    亚型

    IgG1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    Is recommended as capture mAbs in ELISpot, FluoroSpot, and ELISA for analysis of: IL-12/-23 (p40) in combination with mAb ABIN6963861 and ABIN7448304 .

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5 mg/mL

    缓冲液

    supplied at 0.5 mg/mL in PBS with 0.02 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store product at 4-8°C or frozen at -20°C or below. Avoid repeated freezing/ thawing.

    有效期

    18 months
  • Pourakbari, Hosseinpour Sadeghi, Mahmoudi, Parvaneh, Keshavarz Valian, Mamishi: "Evaluation of interleukin-12 receptor β1 and interferon gamma receptor 1 deficiency in patients with disseminated BCG infection." in: Allergologia et immunopathologia, Vol. 47, Issue 1, pp. 38-42, (2019) (PubMed).

    Iaconelli, Lemetais, Kechaou, Chain, Bermúdez-Humarán, Langella, Gervais, Beney: "Drying process strongly affects probiotics viability and functionalities." in: Journal of biotechnology, Vol. 214, pp. 17-26, (2016) (PubMed).

    Myers, Cooper, Kem, Stavrakis, Kosanke, Shevach, Fairweather, Stoner, Cox, Cunningham: "Cardiac myosin-Th17 responses promote heart failure in human myocarditis." in: JCI insight, Vol. 1, Issue 9, (2016) (PubMed).

    Mohanram, Sköld, Bächle, Pathak, Spetz: "IFN-α induces APOBEC3G, F, and A in immature dendritic cells and limits HIV-1 spread to CD4+ T cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 190, Issue 7, pp. 3346-53, (2013) (PubMed).

  • 抗原

    IL12/23 (p40), IL23, IL12 (p70)

    基因ID

    3592, 3593
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