TCR beta 抗体
Quick Overview for TCR beta 抗体 (ABIN6961770)
抗原
See all TCR beta 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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纯化方法
- This monoclonal antibody preparation was purified from tissue culture supernatant via affinity chromatography. For In Vivo Ready™ (IVR) products, each preparation is also evaluated for endotoxin levels using the LAL assay. It is recommended to store the product undiluted at 4°C. Do not freeze.
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亚型
- IgG
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anti-T Cell Receptor (TCR) beta (TCR beta) antibody (FITC)
TCR beta 适用: 小鼠 FACS 宿主: Armenian Hamster Monoclonal H57-597 FITC
anti-T Cell Receptor (TCR) beta (TCR beta) antibody (APC)TCR beta 适用: 小鼠 FACS 宿主: Armenian Hamster Monoclonal H57-597 APC
anti-T Cell Receptor (TCR) beta (TCR beta) (Internal Region) antibodyTCR beta 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-T Cell Receptor (TCR) beta (TCR beta) antibodyTCR beta 适用: 小鼠 FACS, IP 宿主: 仓鼠 Monoclonal H57-597 unconjugated
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应用备注
- This purified format is guaranteed to be >90 % pure as determined by SDS-PAGE analysis.
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说明
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0.5 mg/mL
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限制
- 仅限研究用
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缓冲液
- 10 mM NaH2PO4, 150 mM NaCl, 0.09 % Sodium azide, pH 7.2
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- 2-8°C
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有效期
- 12 months
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- TCR beta (T Cell Receptor (TCR) beta (TCR beta))
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别名
- TCR beta
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背景
- The H57-597 antibody is specific for the beta chain of the mouse T cell Receptor (TCR). This cell surface protein combines with a second protein chain (alpha chain) to form the alpha-beta TCR that is expressed by NK1.1+ thymocytes, NKT cells, and the majority of peripheral T cells. A small number of T cells may express an alternative heteromer of gamma and delta protein chains, known as the gamma-delta TCR. These receptors participate in a complex with CD3, and with the co-receptors CD4 or CD8, to recognize and respond to antigens bound to MHC molecules on antigen-presenting cells. Such interactions promote T cell receptor signaling (T cell activation) and can re- sult in a number of cellular responses including proliferation, differentiation, production of cytokines or activation-induced cell death.The H57-597 antibody is used as a phenotypic marker for T cells expressing the alpha-beta TCR. It is also widely used to cross-link surface TCR and thereby mimic TCR-mediated cell activation or induction of apoptosis. The antibody does not cross-react with cells expressing the gamma-delta TCR.
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基因ID
- 21577
抗原
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