NK-1.1/CD161c 抗体
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北京 101111
Quick Overview for NK-1.1/CD161c 抗体 (ABIN6961768)
抗原
适用
宿主
克隆类型
标记
应用范围
克隆位点
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纯化方法
- This monoclonal antibody preparation was purified from tissue culture supernatant via affinity chromatography. For In Vivo Ready™ (IVR) products, each preparation is also evaluated for endotoxin levels using the LAL assay. It is recommended to store the product undiluted at 4°C. Do not freeze.
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亚型
- IgG2a kappa
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anti-NK-1.1 (AA 101-200) antibody
适用: 小鼠, 人 FACS, WB, IF (cc), IHC (p), ELISA 宿主: 兔 Polyclonal unconjugated
anti-NK-1.1 antibody (PerCP-Cy5.5)适用: 小鼠 FACS 宿主: 小鼠 Monoclonal PK136 PerCP-Cy5.5
anti-NK-1.1 antibody (PE-Cy7)适用: 小鼠 FACS 宿主: 小鼠 Monoclonal PK136 PE-Cy7
anti-NK-1.1 antibody适用: 小鼠 FACS, IP, CyTox 宿主: 小鼠 Monoclonal PK136 unconjugated
anti-NK-1.1 antibody适用: 小鼠 FACS 宿主: 小鼠 Monoclonal PK136 unconjugated
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应用备注
- This purified format is guaranteed to be >90 % pure as determined by SDS-PAGE analysis.
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说明
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0.5 mg/mL
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限制
- 仅限研究用
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缓冲液
- 10 mM NaH2PO4, 150 mM NaCl, 0.09 % Sodium azide, pH 7.2
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- 2-8°C
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有效期
- 12 months
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- NK-1.1/CD161c (NK-1.1)
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别名
- NK1.1 (CD161)
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背景
- The PK136 antibody is specific for mouse NK1.1, a type II transmembrane lectin-like receptor and member of the killer cell lectin-like receptor (KLR) family. NK1.1 is prominently expressed on natural killer (NK) cells, and is correlated with NK cytotoxic effects toward virus-infected cells and tumor cells. NK1.1 is expressed on subsets of NKT cells in certain mouse strains (C57BL/6, FVB/N, and NZB), yet absent from others (AKR, BALB/c, CBA/J, C3H, DBA/1, DBA/2, NOD, SJL, and 129). Putative subsets of NK cells and their expression of NK1.1 antigen are of continuing interest, including NK1.1+/CD117+ (c-Kit) cells reported to be immunosuppressive for CD8+ T cells in a mechanism involving PD-1 and PD-L1. (Ehlers et al. 2012. Endocrinology. 10: 1247.)The PK136 antibody may be used for detection of NK1.1 expression on mouse strains including CE, B6, NZB, C58, Ma/My, ST, SJL, and FVB. The antibody is reported to react with an epitope common to NKR-P1B and NKR-P1C alloantigenic forms of NK1.1 (Carlyle et al. 2006. J. Immunol. 176: 7511-7524).
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基因ID
- 17059
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UniProt
- P27814
抗原
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