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CD86 抗体

CD86 适用: 小鼠 FACS, IF, IHC (fro) 宿主: 大鼠 Monoclonal GL-1 (GL1) unconjugated
产品编号 ABIN6961751
发货至: 中国
  • 抗原 See all CD86 抗体
    CD86
    适用
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    小鼠
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    大鼠
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    单克隆
    标记
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    This CD86 antibody is un-conjugated
    应用范围
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    Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))
    纯化方法
    This monoclonal antibody preparation was purified from tissue culture supernatant via affinity chromatography. For In Vivo Ready™ (IVR) products, each preparation is also evaluated for endotoxin levels using the LAL assay. It is recommended to store the product undiluted at 4°C. Do not freeze.
    克隆位点
    GL-1 (GL1)
    亚型
    IgG2a kappa
    Top Product
    Discover our top product CD86 Primary Antibody
  • 应用备注
    This purified format is guaranteed to be >90 % pure as determined by SDS-PAGE analysis.
    说明

    0.5 mg/mL

    限制
    仅限研究用
  • 缓冲液
    10 mM NaH2PO4, 150 mM NaCl, 0.09 % Sodium azide, pH 7.2
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    2-8°C
    有效期
    12 months
  • 抗原
    CD86
    别名
    CD86 (B7-2) (CD86 产品)
    别名
    B7-2 antibody, B7.2 antibody, B70 antibody, CD28LG2 antibody, LAB72 antibody, B7 antibody, CLS1 antibody, Cd28l2 antibody, ETC-1 antibody, Ly-58 antibody, Ly58 antibody, MB7 antibody, MB7-2 antibody, TS/A-2 antibody, CD86 molecule antibody, CD86 antigen antibody, integrin subunit alpha 2b antibody, CD86 antibody, Cd86 antibody, Itga2b antibody
    背景
    The GL-1 antibody reacts with mouse CD86, also known as B7-2, an 80 kDa cell surface protein which is a ligand for CD28, a co-stim- ulatory receptor for the T cell receptor (TCR). CD28 can also bind a second B7 ligand known as CD80 (B7-1). Both CD80 and CD86 are expressed on activated B cells and antigen-presenting cells. These ligands trigger CD28 signaling in concert with TCR activation to drive T cell proliferation, induce high-level expression of IL-2, impart resistance to apoptosis, and enhance T cell cytotoxicity. The interac- tion / co-stimulatory signaling between the B7 ligands and CD28 provides crucial communication between T cells and B cells or APCs to coordinate the adaptive immune response. The GL-1 antibody may be used as a marker for CD86 expression on B cells, macrophages, and dendritic cells.
    基因ID
    12524
    UniProt
    P42082
    途径
    TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
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