电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

CD86 抗体

This anti-CD86 antibody is a 大鼠 单克隆 antibody detecting CD86 in FACS, IF 和 IHC (fro). Suitable for 小鼠.
产品编号 ABIN6961751
发货至: 中国

Quick Overview for CD86 抗体 (ABIN6961751)

抗原

See all CD86 抗体
CD86

适用

  • 169
  • 132
  • 76
  • 19
  • 10
  • 9
  • 6
  • 4
  • 4
  • 3
  • 2
  • 2
小鼠

宿主

  • 96
  • 92
  • 59
大鼠

克隆类型

  • 179
  • 64
  • 2
单克隆

标记

  • 101
  • 23
  • 18
  • 17
  • 10
  • 5
  • 5
  • 4
  • 4
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This CD86 antibody is un-conjugated

应用范围

  • 173
  • 113
  • 69
  • 56
  • 55
  • 40
  • 30
  • 25
  • 22
  • 20
  • 18
  • 16
  • 14
  • 13
  • 10
  • 5
  • 5
  • 4
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))

克隆位点

GL-1 (GL1)
  • 纯化方法

    This monoclonal antibody preparation was purified from tissue culture supernatant via affinity chromatography. For In Vivo Ready™ (IVR) products, each preparation is also evaluated for endotoxin levels using the LAL assay. It is recommended to store the product undiluted at 4°C. Do not freeze.

    亚型

    IgG2a kappa
  • 应用备注

    This purified format is guaranteed to be >90 % pure as determined by SDS-PAGE analysis.

    说明

    0.5 mg/mL

    限制

    仅限研究用
  • 缓冲液

    10 mM NaH2PO4, 150 mM NaCl, 0.09 % Sodium azide, pH 7.2

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    2-8°C

    有效期

    12 months
  • 抗原

    CD86

    别名

    CD86 (B7-2)

    背景

    The GL-1 antibody reacts with mouse CD86, also known as B7-2, an 80 kDa cell surface protein which is a ligand for CD28, a co-stim- ulatory receptor for the T cell receptor (TCR). CD28 can also bind a second B7 ligand known as CD80 (B7-1). Both CD80 and CD86 are expressed on activated B cells and antigen-presenting cells. These ligands trigger CD28 signaling in concert with TCR activation to drive T cell proliferation, induce high-level expression of IL-2, impart resistance to apoptosis, and enhance T cell cytotoxicity. The interac- tion / co-stimulatory signaling between the B7 ligands and CD28 provides crucial communication between T cells and B cells or APCs to coordinate the adaptive immune response. The GL-1 antibody may be used as a marker for CD86 expression on B cells, macrophages, and dendritic cells.

    基因ID

    12524

    UniProt

    P42082

    途径

    TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
You are here:
Chat with us!