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- 抗原 See all NK-1.1/CD161c products
- NK-1.1/CD161c (NK-1.1)
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适用
- 小鼠
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This NK-1.1/CD161c antibody is conjugated to PerCP-Cy5.5
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应用范围
- Flow Cytometry (FACS)
- 纯化方法
- This monoclonal antibody was purified from tissue culture supernatant via affinity chromatography. The purified antibody was conjugated under optimal conditions, with unreacted dye removed from the preparation. It is recommended to store the product undiluted at 4°C, and protected from prolonged exposure to light. Do not freeze.
- 克隆位点
- PK136
- 亚型
- IgG2a kappa
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anti-NK-1.1 (AA 101-200) antibody
适用: 小鼠, 人 FACS, WB, IF (cc), IHC (p), ELISA 宿主: 兔 Polyclonal unconjugated
anti-NK-1.1 antibody (PE)适用: 小鼠 FACS 宿主: 小鼠 Monoclonal PK136 PE
anti-NK-1.1 antibody (PE-Cy7)适用: 小鼠 FACS 宿主: 小鼠 Monoclonal PK136 PE-Cy7
anti-NK-1.1 antibody适用: 小鼠 FACS, IP, CyTox 宿主: 小鼠 Monoclonal PK136 unconjugated
anti-NK-1.1 antibody适用: 小鼠 FACS 宿主: 小鼠 Monoclonal PK136 unconjugated
anti-NK-1.1 antibody (FITC)适用: 小鼠 FACS 宿主: 小鼠 Monoclonal PK136 FITC
anti-NK-1.1 antibody (APC)适用: 小鼠 FACS 宿主: 小鼠 Monoclonal PK136 APC
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- 应用备注
- This antibody preparation has been quality-tested for flow cytometry using mouse spleen cells, or an appropriate cell type (where indi- cated). The amount of antibody required for optimal staining of a cell sample should be determined empirically in your system.
- 说明
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0.2 mg/mL
- 限制
- 仅限研究用
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- 缓冲液
- 10 mM NaH2PO4, 150 mM NaCl, 0.09 % Sodium azide, 0.1 % gelatin, pH 7.2
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- 2-8°C protected from light
- 有效期
- 12 months
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- 抗原
- NK-1.1/CD161c (NK-1.1)
- 别名
- NK1.1 (CD161) (NK-1.1/CD161c 产品)
- 背景
- The PK136 antibody is specific for mouse NK1.1, a type II transmembrane lectin-like receptor and member of the killer cell lectin-like receptor (KLR) family. NK1.1 is prominently expressed on natural killer (NK) cells, and is correlated with NK cytotoxic effects toward virus-infected cells and tumor cells. NK1.1 is expressed on subsets of NKT cells in certain mouse strains (C57BL/6, FVB/N, and NZB), yet absent from others (AKR, BALB/c, CBA/J, C3H, DBA/1, DBA/2, NOD, SJL, and 129). Putative subsets of NK cells and their expression of NK1.1 antigen are of continuing interest, including NK1.1+/CD117+ (c-Kit) cells reported to be immunosuppressive for CD8+ T cells in a mechanism involving PD-1 and PD-L1 (Ehlers et al. 2012. Endocrinology. 10: 1247).. The PK136 antibody may be used for detection of NK1.1 expression on mouse strains including CE, B6, NZB, C58, Ma/My, ST, SJL, and FVB. The antibody is reported to react with an epitope common to NKR-P1B and NKR-P1C alloantigenic forms of NK1.1 (Carlyle et al. 2006. J. Immunol. 176: 7511-7524).
- 基因ID
- 17059
- UniProt
- P27814
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