ITGAL 抗体 (PerCP-Cy5.5)
Quick Overview for ITGAL 抗体 (PerCP-Cy5.5) (ABIN7278456)
抗原
See all ITGAL 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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纯化方法
- This monoclonal antibody was purified from tissue culture supernatant via affinity chromatography. The purified antibody was conjugated under optimal conditions, with unreacted dye removed from the preparation. It is recommended to store the product undiluted at 4°C, and protected from prolonged exposure to light. Do not freeze.
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亚型
- IgG2a kappa
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应用备注
- This antibody preparation has been quality-tested for flow cytometry using mouse spleen cells, or an appropriate cell type (where indicated). Please refer to the figure legend for the optimal concentration used to stain the tissue shown. We recommend titrating the antibody under your specific conditions to determine the optimal concentration of antibody needed in your experimental system.
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说明
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0.2 mg/mL
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限制
- 仅限研究用
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缓冲液
- 10 mM NaH2PO4, 150 mM NaCl, 0.09 % Sodium azide, 0.1 % gelatin, pH 7.2
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- 2-8°C protected from light
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有效期
- 12 months
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- ITGAL (Integrin alpha-L (ITGAL))
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别名
- CD11a
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背景
- The M17/4 monoclonal antibody reacts with mouse CD11a, an 180kD glycoprotein that is also known as integrin alpha L (ITGAL). CD11a associates non- covalently with CD18 (integrein beta 2) to form the lymphocyte function associated antigen-1 (LFA-1) heterodimer. CD11a is expressed on the cell surface of all leukocytes. LFA-1 plays a critical role in intercellular adhesion that is mediated through interactions with its ligands, ICAM-1 (CD54), ICAM-2 (CD102), and ICAM -3 (CD50). LFA-1 also functions in lymphocyte costimulatory signaling. On resting cells, LFA-1 exists in a low-affinity conformation that is rapidly induced to the high-affinity conformation following cell stimulation.
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基因ID
- 16408
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途径
- Activated T Cell Proliferation, Integrin Complex
抗原
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