NK-1.1/CD161c 抗体
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- 抗原 See all NK-1.1/CD161c products
- NK-1.1/CD161c (NK-1.1)
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适用
- 小鼠
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This NK-1.1/CD161c antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS), Immunoprecipitation (IP), Immunofluorescence (IF), Functional Studies (Func), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 纯化方法
- This monoclonal antibody preparation was purified from tissue culture supernatant via affinity chromatography. For In Vivo Ready™ (IVR) products, each preparation is also evaluated for endotoxin levels using the LAL assay. It is recommended to store the product undiluted at 4°C. Do not freeze.
- 内毒素水平
- Low endotoxin: < 0.01 EU/ug
- 克隆位点
- PK136
- 亚型
- IgG2a kappa
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anti-NK-1.1 (AA 101-200) antibody
适用: 小鼠, 人 FACS, WB, IF (cc), IHC (p), ELISA 宿主: 兔 Polyclonal unconjugated
anti-NK-1.1 antibody (PerCP-Cy5.5)适用: 小鼠 FACS 宿主: 小鼠 Monoclonal PK136 PerCP-Cy5.5
anti-NK-1.1 antibody (PE)适用: 小鼠 FACS 宿主: 小鼠 Monoclonal PK136 PE
anti-NK-1.1 antibody (PE-Cy7)适用: 小鼠 FACS 宿主: 小鼠 Monoclonal PK136 PE-Cy7
anti-NK-1.1 antibody (FITC)适用: 小鼠 FACS 宿主: 小鼠 Monoclonal PK136 FITC
anti-NK-1.1 antibody适用: 小鼠 FACS 宿主: 小鼠 Monoclonal PK136 unconjugated
anti-NK-1.1 antibody (APC)适用: 小鼠 FACS 宿主: 小鼠 Monoclonal PK136 APC
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- 应用备注
- This purified format is guaranteed to be >90 % pure as determined by SDS-PAGE analysis.
- 说明
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2 mg/mL
- 限制
- 仅限研究用
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- 缓冲液
- 10 mM NaH2PO4, 150 mM NaCl, pH 7.2
- 储存液
- Azide free
- 储存条件
- 4 °C
- 储存方法
- 2-8°C
- 有效期
- 12 months
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- 抗原
- NK-1.1/CD161c (NK-1.1)
- 别名
- NK1.1 (CD161) (NK-1.1/CD161c 产品)
- 别名
- AI462337 antibody, CD161 antibody, Ly-59 antibody, Ly55c antibody, Ly59 antibody, NK-RP1 antibody, NK1.1 antibody, NKR-P1.9 antibody, NKRP1 antibody, NKRP140 antibody, Nk-1 antibody, Nk-1.2 antibody, Nk1 antibody, Nk1.2 antibody, Nkrp1c antibody, ly-55c antibody, killer cell lectin-like receptor subfamily B member 1C antibody, Klrb1c antibody
- 背景
- The PK136 antibody is specific for mouse NK1.1, a type II transmembrane lectin-like receptor and member of the killer cell lectin-like receptor (KLR) family. NK1.1 is prominently expressed on natural killer (NK) cells, and is correlated with NK cytotoxic effects toward virus-infected cells and tumor cells. NK1.1 is expressed on subsets of NKT cells in certain mouse strains (C57BL/6, FVB/N, and NZB), yet absent from others (AKR, BALB/c, CBA/J, C3H, DBA/1, DBA/2, NOD, SJL, and 129). Putative subsets of NK cells and their expression of NK1.1 antigen are of continuing interest, including NK1.1+/CD117+ (c-Kit) cells reported to be immunosuppressive for CD8+ T cells in a mechanism involving PD-1 and PD-L1. (Ehlers et al. 2012. Endocrinology. 10: 1247.)The PK136 antibody may be used for detection of NK1.1 expression on mouse strains including CE, B6, NZB, C58, Ma/My, ST, SJL, and FVB. The antibody is reported to react with an epitope common to NKR-P1B and NKR-P1C alloantigenic forms of NK1.1 (Carlyle et al. 2006. J. Immunol. 176: 7511-7524).
- 基因ID
- 17059
- UniProt
- P27814
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