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Catalase 抗体 (AA 23-226)

This anti-Catalase antibody (ABIN6961050) is a Rabbit Monoclonal antibody detecting Catalase in ELISA, IP, IF, FACS. Suitable for Human.
产品编号 ABIN6961050
发货至: 中国

Quick Overview for Catalase 抗体 (AA 23-226) (ABIN6961050)

抗原

See all Catalase (CAT) 抗体
Catalase (CAT)

适用

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宿主

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克隆类型

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单克隆

标记

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This Catalase antibody is un-conjugated

应用范围

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ELISA, Immunoprecipitation (IP), Immunofluorescence (IF), Flow Cytometry (FACS)

克隆位点

DM9
  • 抗原表位

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    AA 23-226

    纯化方法

    Purified from cell culture supernatant by affinity chromatography

    免疫原

    Recombinant human CS1 (Ser23-Met226) (ABIN6961075) produced by using human HEK293 cells

    亚型

    IgG
  • 应用备注

    Flow Cyt  1/100

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    50 % Glycerol, PBS, pH 7.4, 0.1 % BSA, 0.1 % Procline 300

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

    有效期

    12 months
  • 抗原

    Catalase (CAT)

    别名

    CS1

    背景

    Self-ligand receptor of the signaling lymphocytic activation molecule (SLAM) family. SLAM receptors triggered by homo- or heterotypic cell-cell interactions are modulating the activation and differentiation of a wide variety of immune cells and thus are involved in the regulation and interconnection of both innate and adaptive immune response. Activities are controlled by presence or absence of small cytoplasmic adapter proteins, SH2D1A/SAP and/or SH2D1B/EAT-2. Isoform 1 mediates NK cell activation through a SH2D1A-independent extracellular signal-regulated ERK-mediated pathway (PubMed:11698418). Positively regulates NK cell functions by a mechanism dependent on phosphorylated SH2D1B. Downstream signaling implicates PLCG1, PLCG2 and PI3K (PubMed:16339536). In addition to heterotypic NK cells-target cells interactions also homotypic interactions between NK cells may contribute to activation. However, in the absence of SH2D1B, inhibits NK cell function. Acts also inhibitory in T-cells (By similarity). May play a role in lymphocyte adhesion (PubMed:11802771). In LPS-activated monocytes negatively regulates production of proinflammatory cytokines (PubMed:23695528).

    分子量

    37 kDa

    基因ID

    57823

    UniProt

    Q9NQ25

    途径

    Cellular Glucan Metabolic Process, Cell RedoxHomeostasis, Photoperiodism
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