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SIRPA 抗体 (AA 31-370)

This anti-SIRPA antibody is a 兔 单克隆 antibody detecting SIRPA in FACS, ELISA, IP 和 IF. Suitable for 人.
产品编号 ABIN6961045
发货至: 中国

Quick Overview for SIRPA 抗体 (AA 31-370) (ABIN6961045)

抗原

See all SIRPA 抗体
SIRPA (Signal-Regulatory Protein alpha (SIRPA))

适用

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宿主

  • 67
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  • 1
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克隆类型

  • 61
  • 47
  • 1
单克隆

标记

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  • 1
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This SIRPA antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), ELISA, Immunoprecipitation (IP), Immunofluorescence (IF)

克隆位点

DM8
  • 抗原表位

    • 16
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    AA 31-370

    纯化方法

    Purified from cell culture supernatant by affinity chromatography

    免疫原

    Recombinant human SIRPalpha (Glu31-Arg370) (ABIN6961082) produced by using human HEK293 cells

    亚型

    IgG
  • 应用备注

    Flow Cyt  1/100, IP 1/30

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    50 % Glycerol, PBS, pH 7.4, 0.1 % BSA, 0.1 % Procline 300

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

    有效期

    12 months
  • 抗原

    SIRPA (Signal-Regulatory Protein alpha (SIRPA))

    别名

    SIRPalpha

    背景

    The protein encoded by this gene is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. This protein can be phosphorylated by tyrosine kinases. The phospho-tyrosine residues of this PTP have been shown to recruit SH2 domain containing tyrosine phosphatases (PTP), and serve as substrates of PTPs. This protein was found to participate in signal transduction mediated by various growth factor receptors. CD47 has been demonstrated to be a ligand for this receptor protein. This gene and its product share very high similarity with several other members of the SIRP family. These related genes are located in close proximity to each other on chromosome 20p13. Multiple alternatively spliced transcript variants have been determined for this gene.

    分子量

    55 kDa

    基因ID

    140885

    UniProt

    P78324
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