Recombinant SARS-Coronavirus Nucleocapsid Protein (SARS-CoV N) (AA 1-419) 抗体
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Quick Overview for Recombinant SARS-Coronavirus Nucleocapsid Protein (SARS-CoV N) (AA 1-419) 抗体 (ABIN6953156)
抗原
See all SARS-Coronavirus Nucleocapsid Protein (SARS-CoV N) 抗体抗体类型
片段
适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-419
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原理
- N Recombinant Monoclonal Antibody
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产品特性
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Recombinant anti-SARS-CoV-2 Nucleoprotein Mouse ScFv is expressed from 293 cells (HEK293), It is a chimeric monoclonal antibody combining the mouse variable regions with the constant domains of human IgG1.
Monoclonal mouse (varialbe region)/human (kappa/IgG1 constant)chimeric antibody -
纯化方法
- Affinity-chromatography
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免疫原
- Recombinant Human Novel Coronavirus Nucleoprotein (N) (1-419aa)(CSB-EP3325GMY)
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亚型
- Ig kappa, IgG1
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anti-SARS-Coronavirus Nucleocapsid Protein (SARS-CoV N) antibody
SARS-CoV N 适用: SARS Coronavirus (SARS-CoV), SARS Coronavirus-2 (SARS-CoV-2) ELISA, WB, IHC, FACS, FM 宿主: 兔 Polyclonal unconjugated
anti-SARS-Coronavirus Nucleocapsid Protein (SARS-CoV N) (AA 1-419) antibody (Fc Tag)SARS-CoV N 适用: SARS Coronavirus-2 (SARS-CoV-2) ELISA, WB, GICA 宿主: 小鼠 Chimeric 1A6 Fc Tag scFv fragment Recombinant Antibody
anti-SARS-Coronavirus Nucleocapsid Protein (SARS-CoV N) antibodySARS-CoV N 适用: SARS Coronavirus (SARS-CoV) ELISA, WB 宿主: 小鼠 Monoclonal 14B3D unconjugated
anti-SARS-Coronavirus Nucleocapsid Protein (SARS-CoV N) (AA 1-419) antibody (Fc Tag,HRP)SARS-CoV N 适用: SARS Coronavirus-2 (SARS-CoV-2) ELISA 宿主: 小鼠 Monoclonal 1A6 Fc Tag,HRP scFv fragment Recombinant Antibody
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应用备注
- ELISA:1:10000-1:50000, GICA:1:500-1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze
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- SARS-Coronavirus Nucleocapsid Protein (SARS-CoV N)
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别名
- SARS-CoV-2 (SARS-CoV-2/ 2019-nCoV) N
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背景
- Nucleoprotein packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M. It plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication. Coronavirus nucleoproteins are phosphoproteins, and are encoded near the 3' end of the genome. N possesses two RNA-binding domains: an N-terminal domain with adjacent S/R-rich motif and the C-terminal 209 amino acids. N protein is invovled in coronavirus infection with many ways: the C-terminal domain (CTD) of N is important for binding the genomic RNA packaging signal leading to selective genome incorporation, the N3 domain interacts with the endodomain of M to form virions, and the serine-arginine repeat region of N (SR) interacts with the first ubiquitin-like domain of nsp3 in a critical early replication step. Moreover, it has also been demonstrated that N can oligomerize through interactions in the CTD, bind viral RNA through the N-terminal domain, unwind double-stranded nucleic acid in the manner of an RNA chaperone, and pack in a helix through the N-terminal domain, though none of these other functions has yet been demonstrated to be important for infection.
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UniProt
- P0DTC9
抗原
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