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Recombinant SARS-CoV-2 Spike 抗体 (AA 16-685) (Fc Tag,HRP)

This 小鼠单克隆 antibody specifically detects SARS-CoV-2 Spike in ELISA. It exhibits reactivity toward SARS Coronavirus-2 (SARS-CoV-2).It has been mentioned in 1 publication

ELISA

1 image

(1 reference)

产品编号 ABIN6953153

发货至: 中国

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Quick Overview for Recombinant SARS-CoV-2 Spike 抗体 (AA 16-685) (Fc Tag,HRP) (ABIN6953153)

抗原

See all SARS-CoV-2 Spike (SARS-CoV-2 S) 抗体

SARS-CoV-2 Spike (SARS-CoV-2 S)

抗体类型

Recombinant Antibody

片段

scFv fragment

适用

SARS Coronavirus-2 (SARS-CoV-2)

宿主

小鼠

克隆类型

单克隆

标记

This SARS-CoV-2 Spike antibody is conjugated to Fc Tag,HRP

应用范围

ELISA

克隆位点

Discover our top product SARS-CoV-2 S Primary Antibody

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AA 16-685

原理

S Recombinant Monoclonal Antibody, HRP conjugated

产品特性

Recombinant anti-SARS-CoV-2 spike Mouse ScFv is expressed from 293 cells (HEK293) with a human IgG1 Fc tag on C-terminal.
Mouse scFv fusion with human IgG1 Fc
AA 16-685

纯化方法

Affinity-chromatography

免疫原

Recombinant Human Novel Coronavirus Spike glycoprotein (S) (16-685aa) (CSB-MP3324GMY)

亚型

IgG1
anti-SARS-CoV-2 Spike (SARS-CoV-2 S) (C-Term) antibody
SARS-CoV-2 S 适用: SARS Coronavirus-2 (SARS-CoV-2), SARS Coronavirus (SARS-CoV) ELISA, WB, IF, IHC 宿主: 兔 Polyclonal unconjugated

anti-SARS-CoV-2 Spike (SARS-CoV-2 S) antibody
SARS-CoV-2 S 适用: SARS Coronavirus-2 (SARS-CoV-2), SARS CoV-2 Alpha, SARS CoV-2 Beta, SARS CoV-2 Gamma ELISA, WB 宿主: 兔 Polyclonal unconjugated

anti-SARS-CoV-2 Spike (SARS-CoV-2 S) (AA 319-541) antibody
Animal-Free SARS-CoV-2 S 适用: SARS Coronavirus-2 (SARS-CoV-2) ELISA, WB, FACS, IF 宿主: 小鼠 Monoclonal AB68-A09 unconjugated Recombinant Antibody

anti-SARS-CoV-2 Spike (SARS-CoV-2 S) (AA 319-541), (Receptor Binding Domain) antibody (Fc Tag)
SARS-CoV-2 S 适用: SARS Coronavirus-2 (SARS-CoV-2) ELISA, Neut, GICA 宿主: Human Monoclonal A1 Fc Tag single-domain Antibody (sdAb) Recombinant Antibody

anti-SARS-CoV-2 Spike (SARS-CoV-2 S) antibody
SARS-CoV-2 S 适用: SARS Coronavirus-2 (SARS-CoV-2) ELISA 宿主: Human Monoclonal AM015553 (553-15) unconjugated Recombinant Antibody

anti-SARS-CoV-2 Spike (SARS-CoV-2 S) antibody
SARS-CoV-2 S 适用: SARS Coronavirus-2 (SARS-CoV-2) ELISA, WB 宿主: Human Monoclonal AM004414 (414-4) unconjugated Recombinant Antibody

anti-SARS-CoV-2 Spike (SARS-CoV-2 S) (AA 319-541), (RBD) antibody
SARS-CoV-2 S 适用: SARS Coronavirus-2 (SARS-CoV-2) ELISA, FACS 宿主: 兔 Monoclonal DM54 unconjugated

anti-SARS-CoV-2 Spike (SARS-CoV-2 S) (AA 16-685) antibody
SARS-CoV-2 S 适用: SARS Coronavirus-2 (SARS-CoV-2) ELISA, GICA 宿主: Chimeric Chimeric H6 unconjugated Recombinant Antibody

anti-SARS-CoV-2 Spike (SARS-CoV-2 S) (AA 16-685) antibody (Fc Tag,Biotin)
SARS-CoV-2 S 适用: SARS Coronavirus-2 (SARS-CoV-2) ELISA 宿主: 小鼠 Monoclonal H6 Fc Tag,Biotin scFv fragment Recombinant Antibody

anti-SARS-CoV-2 Spike (SARS-CoV-2 S) (RBD) antibody
SARS-CoV-2 S 适用: SARS Coronavirus-2 (SARS-CoV-2) WB 宿主: 山羊 Polyclonal unconjugated

应用备注

ELISA:1:10000-1:50000

限制

仅限研究用
状态

Liquid

缓冲液

Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

储存液

ProClin

注意事项

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C,-80 °C

储存方法

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze
Wu, Cong, Wei, Hu, Sun, Ran, Liao, Zheng, Ye: "A Naïve Phage Display Library-Derived Nanobody Neutralizes SARS-CoV-2 and Three Variants of Concern." in: International journal of nanomedicine, Vol. 18, pp. 5781-5795, (2023) (PubMed).
抗原

SARS-CoV-2 Spike (SARS-CoV-2 S)

别名

SARS-CoV-2 (SARS-CoV-2/ 2019-nCoV) S

物质类

Viral Protein

背景

Spike glycoprotein comprises two functional subunits responsible for binding to the host cell receptor (S1 subunit) and fusion of the viral and cellular membranes (S2 subunit). For many coronavirus (CoVs), S is cleaved at the boundary between the S1 and S2 subunits, which remain non-covalently bound in the prefusion conformation. The distal S1 subunit comprises the receptor-binding domain(s) and contributes to stabilization of the prefusion state of the membrane-anchored S2 subunit that contains the fusion machinery. S is further cleaved by host proteases at the so-called S2' site located immediately upstream of the fusion peptide in all CoVs. This cleavage has been proposed to activate the protein for membrane fusion via extensive irreversible conformational changes. However, different CoVs use distinct domains within the S1 subunit to recognize a variety of attachment and entry receptors, depending on the viral species. Endemic human coronaviruses OC43 and HKU1 attach via their S domain A to 5-N-acetyl-9-O-acetyl-sialosides found on glycoproteins and glycolipids at the host cell surface to enable entry into susceptible cells. MERS-CoV S uses domain A to recognize non-acetylated sialoside attachment receptors, which likely promote subsequent binding of domain B to the entry receptor, dipeptidyl-peptidase 4. SARS-CoV and several SARS-related coronaviruses (SARSr-CoV) interact directly with angiotensin-converting enzyme 2 (ACE2) via SB to enter target cells.

基因ID

43740568

UniProt

P0DTC2