SARS-Coronavirus Nucleocapsid Protein (SARS-CoV N) (AA 1-422) 抗体
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Quick Overview for SARS-Coronavirus Nucleocapsid Protein (SARS-CoV N) (AA 1-422) 抗体 (ABIN7072836)
抗原
See all SARS-Coronavirus Nucleocapsid Protein (SARS-CoV N) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-422
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产品特性
- 2019-nCoV CoV Nucleocapsid Has cross-reactivity in ELISA and WB with SARS-CoV Nucleoprotein / NP Protein .
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免疫原
- This antibody was obtained from a rabbit immunized with purified, recombinant SARS-CoV Nucleoprotein / NP ( NP_828858.1, Met1-Ala422).
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应用备注
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WB 1:1000-1:5000
Validated Applications:WB,ELISA,IHC-P,FCM,ICC/IF,IP (Antibody's applications have not been validated with corresponding viruses. Optimal concentrations/dilutions should be determined by the end user.) -
限制
- 仅限研究用
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缓冲液
- 0.2 um filtered solution in PBS
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.
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- SARS-Coronavirus Nucleocapsid Protein (SARS-CoV N)
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别名
- Coronavirus Nucleocapsid Protein
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物质类
- Viral Protein
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背景
- Coronaviruses are enveloped viruses with a positive-sense RNA genome and with a nucleocapsid of helical symmetry. Coronavirus nucleoproteins localize to the cytoplasm and the nucleolus, a subnuclear structure, in both virus-infected primary cells and in cells transfected with plasmids that express N protein. Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. During virion assembly, N protein binds to viral RNA and leads to formation of the helical nucleocapsid. Nucleocapsid protein is a highly immunogenic phosphoprotein also implicated in viral genome replication and in modulating cell signaling pathways. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool.
抗原
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