KDM5C 抗体
Our Local Distributor
北京 101111
Quick Overview for KDM5C 抗体 (ABIN6952407)
抗原
See all KDM5C 抗体适用
宿主
克隆类型
标记
应用范围
-
-
特异性
- Polyclonal antibody raised in rabbit against human JARID1C (Jumonji, AT Rich Interactive Domain 1C), using a synthetic peptide containing a sequence from the central part of the protein
-
交叉反应
- 小鼠
-
纯化方法
- Affinity purified
-
免疫原
- synthetic peptide
-
-
-
-
应用备注
-
ChIP/ChIP-seq 5 μg:ChIP
WB 1:1,000
IP 6 μg:IP -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 0.2 μg/μL
-
缓冲液
- TBS, 0,1 % BSA, 0.05 % azide
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
-
- KDM5C (Lysine (K)-Specific Demethylase 5C (KDM5C))
-
别名
- JARID1C
-
背景
- JARID1C (UniProtKB/Swiss-Prot entry P41229) is a histone demethylase that specifically demethylates tri- and dimethylated Lys-4 of histone H3. It has no activity towards monomethylated H3K4, H3K9, H3K27, H3K36, H3K79 or H4K20. It is involved in transcriptional regulation and chromatin remodeling. JARID1C participates in transcriptional repression of neuronal genes by recruiting histone deacetylases and REST at neuron-restrictive silencer elements. Mutations in JARID1C have been associated with X-linked mental retardation
-
UniProt
- P41229
-
途径
- Warburg Effect
抗原
-