NCOR1 抗体
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北京 101111
Quick Overview for NCOR1 抗体 (ABIN6952398)
抗原
See all NCOR1 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- Polyclonal antibody raised in rabbit against human NCOR1 (Nuclear Receptor Corepressor 1), using a synthetic peptide containing a sequence from the central part of the protein
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交叉反应
- 小鼠
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纯化方法
- Affinity purified
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免疫原
- synthetic peptide
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应用备注
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ChIP/ChIP-seq 2 μg:ChIP
WB 1:5,000
IP 6 μg:IP -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 μg/μL
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缓冲液
- TBS, 0,1 % BSA, 0.05 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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- NCOR1 (Nuclear Receptor Co-Repressor 1 (NCOR1))
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别名
- NCOR1
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背景
- NCOR1 (UniProtKB/Swiss-Prot entry O75376) mediates transcriptional repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. NCOR1 is part of a complex which may impede the access of basal transcription factors.by promoting histone deacetylation and the formation of repressive chromatin structures.
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UniProt
- O75376
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途径
- Nuclear Hormone Receptor Binding, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha, Regulation of Carbohydrate Metabolic Process
抗原
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