CBX2 抗体 (C-Term)
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Quick Overview for CBX2 抗体 (C-Term) (ABIN6952393)
抗原
See all CBX2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- Polyclonal antibody raised in rabbit against human CBX2 (chromobox 2), using a synthetic peptide containing a sequence from the C-terminus of the protein
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纯化方法
- Affinity purified
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免疫原
- synthetic peptide
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应用备注
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ChIP/ChIP-seq 1 μg:ChIP
WB 1:1,000
IP 6 μg:IP -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Tris-citrate/phosphate buffer, 0.05 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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- CBX2 (Chromobox Homolog 2 (CBX2))
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别名
- CBX2
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背景
- CBX2 (UniProtKB/Swiss-Prot entry Q14781) is a component of the PRC1-like polycomb multiprotein complex, which is required to maintain the transcriptionally repressive state of many genes throughout development via chromatin remodeling and modification of histones. The PRC1 complex mediates monoubiquitination of histone H2A on lysine 119, introducing heritably changed expression. CBX2 is involved in sexual development. Mutations in CBX2 are associated with gonadal dysgenesis in humans.
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UniProt
- Q14781
抗原
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