Retinoic Acid Receptor alpha 抗体 (C-Term)
Quick Overview for Retinoic Acid Receptor alpha 抗体 (C-Term) (ABIN6952387)
抗原
See all Retinoic Acid Receptor alpha (RARA) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- Polyclonal antibody raised in rabbit against human RARA (Retinoic Acid Receptor alpha) using two KLH-conjugated synthetic peptides containing sequences from the C-terminal region of the protein.
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纯化方法
- whole antiserum
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免疫原
- synthetic peptide
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应用备注
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ChIP/ChIP-seq 4 μL:ChIP
ELISA 1:50
WB 1:750 -
限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- serum, 0.05 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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- Retinoic Acid Receptor alpha (RARA) (Retinoic Acid Receptor, alpha (RARA))
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别名
- RARA
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背景
- RARA (UniProtKB/Swiss-Prot entry P10276) is a receptor for retinoic acid, a vitamin A metabolite, which directly regulates gene expression in target cells by binding to specific DNA response elements. In the absence of its ligand, this receptor represses transcription through the recruitment of specific corepressors and of HDAC's, whereas binding of retinioc acid causes the recruitment of coactivators and HAT's. Translocations involving the RARA gene, often leading to a RARA/PML fusion protein, are a major cause of acute promyelocytic leukemia.
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UniProt
- P10276
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途径
- Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, S100 Proteins
抗原
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