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HDAC3 抗体 (C-Term)

This anti-HDAC3 antibody is a 兔 多克隆 antibody detecting HDAC3 in ELISA, ChIP 和 ChIP-seq. Suitable for 人.
产品编号 ABIN6952382
发货至: 中国

Quick Overview for HDAC3 抗体 (C-Term) (ABIN6952382)

抗原

See all HDAC3 抗体
HDAC3 (Histone Deacetylase 3 (HDAC3))

适用

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宿主

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克隆类型

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多克隆

标记

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This HDAC3 antibody is un-conjugated

应用范围

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ELISA, Chromatin Immunoprecipitation (ChIP), ChIP DNA-Sequencing (ChIP-seq)
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    C-Term

    特异性

    Polyclonal antibody raised in rabbit against human HDAC3 (Histone deacetylase 3), using two KLH-conjugated synthetic peptides from the central and the C-terminal part of the protein, respectively.

    纯化方法

    Peptide affinity purified

    免疫原

    synthetic peptide
  • 应用备注

    ChIP/ChIP-seq 2 μg:ChIP
    ELISA 1:10,000
    WB not recommended

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1.7 μg/μL

    缓冲液

    PBS, 0.05 % azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C
  • 抗原

    HDAC3 (Histone Deacetylase 3 (HDAC3))

    别名

    HDAC3

    背景

    HDAC3 (UniProt/Swiss-Prot entry O15379) catalyses the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4) and on some other non-histone substrates. Acetylation and deacetylation of these highly conserved lysine residues is important for the control of gene expression. When tethered to a promoter, HDAC3 represses transcription and therefore plays an important role in transcriptional regulation, cell cycle progression and developmental events. HDAC3 probably participates in the regulation of transcription through its binding to the YY1 transcription factor, increasing YY1 repression. HDAC3 also downregulates p53 and is considered a potential tumor suppressor gene.

    UniProt

    O15379

    途径

    Neurotrophin Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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