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BRD4 抗体 (N-Term)

This 兔 多克隆 anti-BRD4 antibody specifically detects BRD4 in WB, ELISA, ChIP 和 ChIP-seq. The antibody is reactive with 人 samples.
产品编号 ABIN6952374
发货至: 中国
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Quick Overview for BRD4 抗体 (N-Term) (ABIN6952374)

抗原

See all BRD4 抗体
BRD4 (Bromodomain Containing 4 (BRD4))

适用

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宿主

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克隆类型

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多克隆

标记

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This BRD4 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Chromatin Immunoprecipitation (ChIP), ChIP DNA-Sequencing (ChIP-seq)
  • 抗原表位

    • 13
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    N-Term

    特异性

    Polyclonal antibody raised in rabbit against human BRD4 (Bromodomain Containing 4), using two KLH-conjugated synthetic peptides from the N-terminal and central part of the protein, respectively.

    纯化方法

    Peptide affinity purified

    免疫原

    synthetic peptide
  • 应用备注

    ChIP 2 μg:ChIP
    ELISA 1:10,000
    WB 1:1,000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    2.6 μg/μL

    缓冲液

    PBS, 0.05 % azide, 0.05 % ProClin300

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C
  • 抗原

    BRD4 (Bromodomain Containing 4 (BRD4))

    别名

    BRD4

    背景

    BRD4 (UniProt/Swiss-Prot entry O60885) is a chromatin reader protein that binds acetylated histones. It remains associated with acetylated chromatin throughout the entire cell cycle and provides epigenetic memory for gene transcription by preserving an acetylated chromatin status. As such, it plays a key role in the transmission of epigenetic memory across cell divisions. BRD4 promotes phosphorylation of Ser-2 of the C-terminal domain (CTD) of RNA polymerase II and plays a key role in regulating the transcription of signal-inducible genes. It has been implicated in a translocation of chromosome 19 which causes an upper respiratory tract carcinoma.

    UniProt

    O60885

    途径

    Chromatin Binding, SARS-CoV-2 Protein Interactome
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