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Claudin 18 抗体

The 小鼠 单克隆 anti-Claudin 18 antibody (ABIN6950837) specifically detects Claudin 18 in IHC. The antibody is reactive with 人 samples.
产品编号 ABIN6950837
发货至: 中国
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Quick Overview for Claudin 18 抗体 (ABIN6950837)

抗原

See all Claudin 18 (CLDN18) 抗体
Claudin 18 (CLDN18)

适用

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人

宿主

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小鼠

克隆类型

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单克隆

标记

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This Claudin 18 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC)
  • 原理

    Claudin 18 mouse mAb

    特异性

    The antibody can specifically recognize both human Claudin 18. 1 and Claudin 18. 2 protein.

    纯化方法

    The antibody was purified by affinity chromatography using a specific immunogen.

    免疫原

    A synthetic peptide corresponding to the amino acid region 150 - 261 of the human Claudin 18 protein.

    亚型

    IgG
  • 应用备注

    IHC, 1:200-1:400

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid freeze / thaw cycles

    储存条件

    -20 °C

    储存方法

    Store at-20°C. Avoid freeze / thaw cycles.
  • 抗原

    Claudin 18 (CLDN18)

    别名

    Claudin 18

    背景

    Synonyms: Claudin 18, Claudin-18, CLD18_HUMAN, CLDN18, SFTA5, SFTPJ

    Background: Claudin 18 is a 27 kDa membrane protein, belonging to the tight junction protein family. It is highly specifically expressed in gastric epithelial cells, and almost not expressed in other normal tissues. Studies have shown that the expression of gastric tissue increases after cancer, and the abnormal expression in pancreatic cancer, lung cancer, esophageal cancer and ovarian cancer promotes the metastasis of cancer cells. Therefore, antibody based drugs against Claudin 18 can significantly improve the survival rate of patients.

    Gene Name: CLDN18

    Protein Name: Claudin 18

    基因ID

    51208

    UniProt

    P56856

    途径

    Cell-Cell Junction Organization, Hepatitis C
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