ACTH 抗体
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北京 101111
Quick Overview for ACTH 抗体 (ABIN6950780)
抗原
See all ACTH 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Adrenocorticotropin (ACTH) mouse mAb
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特异性
- The antibody can specifically recognize human ACTH protein.
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纯化方法
- The antibody was purified by affinity chromatography using a specific immunogen.
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免疫原
- A synthetic peptide corresponding to the amino acid region 100 - 200 of the human Adrenocorticotropin protein.
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亚型
- IgG
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应用备注
- IHC, 1:200-1:400
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid freeze / thaw cycles
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储存条件
- -20 °C
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储存方法
- Store at-20°C. Avoid freeze / thaw cycles.
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- ACTH (Adrenocorticotropic hormone (ACTH))
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别名
- ACTH-Adrenocorticotropin (ACTH)
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背景
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Synonyms: ACTH, Adrenocorticotropic hormone, Adrenocorticotropin, alpha melanocyte stimulating hormone, Alpha MSH, Alpha-MSH, beta endorphin, Beta LPH, beta melanocyte stimulating hormone, Beta MSH, Beta-LPH, Beta-MSH, CLIP, Gamma MSH, Gamma-LPH, Gamma-MSH, Lipotropin beta, Lipotropin gamma, LPH, Melanotropin alpha, Melanotropin, Melanotropin beta, Melanotropin gamma, met enkephalin, MSH, NPP, POC, POMC, pro ACTH endorphin, Proopiomelanocortin, Proopiomelanocortin preproprotein
Background: ACTH is a polypeptide hormone secreted by anterior pituitary cells. ACTH effects adrenal gland to product of cortisol and it also mediates bone formation and osteoblast survival. ACTH antibody is mainly used for functional classification of pituitary tumors and differential diagnosis of primary and metastatic pituitary tumors. Studies have shown that abnormal ACTH products are often related to lung small cell carcinoma, so it can be used to detect the distribution of hormone cells in some neuroendocrine tumors, such as pheochromocytoma and carcinoid.
Gene Name: POMC
Protein Name: Adrenocorticotropin
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基因ID
- 5443
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UniProt
- P01189
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途径
- Metabolism of Steroid Hormones and Vitamin D, Peptide Hormone Metabolism, Hormone Activity
抗原
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